Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers

Yujing He,1 Na Wu1,2 1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, People’ s Republic of China; 2Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Na WuSh...

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Autores principales:	He Y, Wu N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	gestational diabetes mellitus endothelial cells biomarkers Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/98424363815c4a7488f17896a3f7448d
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spelling	oai:doaj.org-article:98424363815c4a7488f17896a3f7448d2021-12-02T13:33:14ZResearch Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers1178-7007https://doaj.org/article/98424363815c4a7488f17896a3f7448d2021-03-01T00:00:00Zhttps://www.dovepress.com/research-progress-on-gestational-diabetes-mellitus-and-endothelial-dys-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Yujing He,1 Na Wu1,2 1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, People’ s Republic of China; 2Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Na WuShengjing Hospital of China, 36 Sanhao Road, Heping District, Shenyang, Liaoning Province, 110004, People’s Republic of ChinaTel +86 18940258445Email 3441535223@qq.comAbstract: Gestational diabetes mellitus (GDM) is the onset or first recognition of diabetes during pregnancy in women with normal glucose metabolism or potentially impaired glucose tolerance before pregnancy. Studies have shown that vascular endothelial cells (VECs) are an important target organ of insulin, which is injured by multiple factors in the case of GDM, thereby leading to worsened insulin resistance (IR) and the further development of GDM. When VECs are abnormal, there will be changes in the content of a variety of cell markers, which may be helpful for the clinical prediction and diagnosis of GDM. This study attempted to investigate the mechanism and markers of VECs injury in GDM patients.Keywords: gestational diabetes mellitus, endothelial cells, biomarkersHe YWu NDove Medical Pressarticlegestational diabetes mellitusendothelial cellsbiomarkersSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 983-990 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	gestational diabetes mellitus endothelial cells biomarkers Specialties of internal medicine RC581-951
spellingShingle	gestational diabetes mellitus endothelial cells biomarkers Specialties of internal medicine RC581-951 He Y Wu N Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers
description	Yujing He,1 Na Wu1,2 1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, People’ s Republic of China; 2Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Na WuShengjing Hospital of China, 36 Sanhao Road, Heping District, Shenyang, Liaoning Province, 110004, People’s Republic of ChinaTel +86 18940258445Email 3441535223@qq.comAbstract: Gestational diabetes mellitus (GDM) is the onset or first recognition of diabetes during pregnancy in women with normal glucose metabolism or potentially impaired glucose tolerance before pregnancy. Studies have shown that vascular endothelial cells (VECs) are an important target organ of insulin, which is injured by multiple factors in the case of GDM, thereby leading to worsened insulin resistance (IR) and the further development of GDM. When VECs are abnormal, there will be changes in the content of a variety of cell markers, which may be helpful for the clinical prediction and diagnosis of GDM. This study attempted to investigate the mechanism and markers of VECs injury in GDM patients.Keywords: gestational diabetes mellitus, endothelial cells, biomarkers
format	article
author	He Y Wu N
author_facet	He Y Wu N
author_sort	He Y
title	Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers
title_short	Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers
title_full	Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers
title_fullStr	Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers
title_full_unstemmed	Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers
title_sort	research progress on gestational diabetes mellitus and endothelial dysfunction markers
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/98424363815c4a7488f17896a3f7448d
work_keys_str_mv	AT hey researchprogressongestationaldiabetesmellitusandendothelialdysfunctionmarkers AT wun researchprogressongestationaldiabetesmellitusandendothelialdysfunctionmarkers
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Research Progress on Gestational Diabetes Mellitus and Endothelial Dysfunction Markers

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