Glial promoter selectivity following AAV-delivery to the immature brain.

Glial promoter selectivity following AAV-delivery to the immature brain.

Recombinant adeno-associated virus (AAV) vectors are versatile tools for gene transfer to the central nervous system (CNS) and proof-of-concept studies in adult rodents have shown that the use of cell type-specific promoters is sufficient to target AAV-mediated transgene expression to glia. However,...

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Autores principales: Georg von Jonquieres, Nadine Mersmann, Claudia Bettina Klugmann, Anne Editha Harasta, Beat Lutz, Orla Teahan, Gary David Housley, Dominik Fröhlich, Eva-Maria Krämer-Albers, Matthias Klugmann
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/984f0a8c0abe433b9effcce3f16e096b
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