The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma

The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma

The rare lung cancer subtype pulmonary lymphoepithelioma-like carcinoma is linked to Epstein-Barr virus infection. Here, the authors provide a mutational landscape for this cancer, showing a low burden of somatic mutations and high prevalence of copy number variations.

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Detalles Bibliográficos
Autores principales: Shaodong Hong, Dongbing Liu, Shuzhen Luo, Wenfeng Fang, Jianhua Zhan, Sha Fu, Yaxiong Zhang, Xuan Wu, Huaqiang Zhou, Xi Chen, Gang Chen, Zhonghan Zhang, Qiufan Zheng, Xiaobo Li, Jinghao Chen, Xingmin Liu, Mengyue Lei, Chen Ye, Jian Wang, Huanming Yang, Xun Xu, Shida Zhu, Yunpeng Yang, Yuanyuan Zhao, Ningning Zhou, Hongyun Zhao, Yan Huang, Lanjun Zhang, Kui Wu, Li Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/9850e0e2e6444fe28807a412984ca961
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Descripción
Sumario:The rare lung cancer subtype pulmonary lymphoepithelioma-like carcinoma is linked to Epstein-Barr virus infection. Here, the authors provide a mutational landscape for this cancer, showing a low burden of somatic mutations and high prevalence of copy number variations.

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