The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma

The rare lung cancer subtype pulmonary lymphoepithelioma-like carcinoma is linked to Epstein-Barr virus infection. Here, the authors provide a mutational landscape for this cancer, showing a low burden of somatic mutations and high prevalence of copy number variations.

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Autores principales: Shaodong Hong, Dongbing Liu, Shuzhen Luo, Wenfeng Fang, Jianhua Zhan, Sha Fu, Yaxiong Zhang, Xuan Wu, Huaqiang Zhou, Xi Chen, Gang Chen, Zhonghan Zhang, Qiufan Zheng, Xiaobo Li, Jinghao Chen, Xingmin Liu, Mengyue Lei, Chen Ye, Jian Wang, Huanming Yang, Xun Xu, Shida Zhu, Yunpeng Yang, Yuanyuan Zhao, Ningning Zhou, Hongyun Zhao, Yan Huang, Lanjun Zhang, Kui Wu, Li Zhang
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9850e0e2e6444fe28807a412984ca961
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spelling oai:doaj.org-article:9850e0e2e6444fe28807a412984ca9612021-12-02T17:33:23ZThe genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma10.1038/s41467-019-10902-w2041-1723https://doaj.org/article/9850e0e2e6444fe28807a412984ca9612019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10902-whttps://doaj.org/toc/2041-1723The rare lung cancer subtype pulmonary lymphoepithelioma-like carcinoma is linked to Epstein-Barr virus infection. Here, the authors provide a mutational landscape for this cancer, showing a low burden of somatic mutations and high prevalence of copy number variations.Shaodong HongDongbing LiuShuzhen LuoWenfeng FangJianhua ZhanSha FuYaxiong ZhangXuan WuHuaqiang ZhouXi ChenGang ChenZhonghan ZhangQiufan ZhengXiaobo LiJinghao ChenXingmin LiuMengyue LeiChen YeJian WangHuanming YangXun XuShida ZhuYunpeng YangYuanyuan ZhaoNingning ZhouHongyun ZhaoYan HuangLanjun ZhangKui WuLi ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shaodong Hong
Dongbing Liu
Shuzhen Luo
Wenfeng Fang
Jianhua Zhan
Sha Fu
Yaxiong Zhang
Xuan Wu
Huaqiang Zhou
Xi Chen
Gang Chen
Zhonghan Zhang
Qiufan Zheng
Xiaobo Li
Jinghao Chen
Xingmin Liu
Mengyue Lei
Chen Ye
Jian Wang
Huanming Yang
Xun Xu
Shida Zhu
Yunpeng Yang
Yuanyuan Zhao
Ningning Zhou
Hongyun Zhao
Yan Huang
Lanjun Zhang
Kui Wu
Li Zhang
The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma
description The rare lung cancer subtype pulmonary lymphoepithelioma-like carcinoma is linked to Epstein-Barr virus infection. Here, the authors provide a mutational landscape for this cancer, showing a low burden of somatic mutations and high prevalence of copy number variations.
format article
author Shaodong Hong
Dongbing Liu
Shuzhen Luo
Wenfeng Fang
Jianhua Zhan
Sha Fu
Yaxiong Zhang
Xuan Wu
Huaqiang Zhou
Xi Chen
Gang Chen
Zhonghan Zhang
Qiufan Zheng
Xiaobo Li
Jinghao Chen
Xingmin Liu
Mengyue Lei
Chen Ye
Jian Wang
Huanming Yang
Xun Xu
Shida Zhu
Yunpeng Yang
Yuanyuan Zhao
Ningning Zhou
Hongyun Zhao
Yan Huang
Lanjun Zhang
Kui Wu
Li Zhang
author_facet Shaodong Hong
Dongbing Liu
Shuzhen Luo
Wenfeng Fang
Jianhua Zhan
Sha Fu
Yaxiong Zhang
Xuan Wu
Huaqiang Zhou
Xi Chen
Gang Chen
Zhonghan Zhang
Qiufan Zheng
Xiaobo Li
Jinghao Chen
Xingmin Liu
Mengyue Lei
Chen Ye
Jian Wang
Huanming Yang
Xun Xu
Shida Zhu
Yunpeng Yang
Yuanyuan Zhao
Ningning Zhou
Hongyun Zhao
Yan Huang
Lanjun Zhang
Kui Wu
Li Zhang
author_sort Shaodong Hong
title The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma
title_short The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma
title_full The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma
title_fullStr The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma
title_full_unstemmed The genomic landscape of Epstein-Barr virus-associated pulmonary lymphoepithelioma-like carcinoma
title_sort genomic landscape of epstein-barr virus-associated pulmonary lymphoepithelioma-like carcinoma
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9850e0e2e6444fe28807a412984ca961
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