High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon

Achieving strain-level resolution is a major obstacle for source tracking and temporal studies of microbiomes. In this study, we describe a novel deep-sequencing approach that provides species- and strain-level resolution of the neonatal microbiome.

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Autores principales: J. Graf, N. Ledala, M. J. Caimano, E. Jackson, D. Gratalo, D. Fasulo, M. D. Driscoll, S. Coleman, A. P. Matson
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/985188f48aa746a1a0c85edf7d900fa1
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spelling oai:doaj.org-article:985188f48aa746a1a0c85edf7d900fa12021-11-03T18:15:37ZHigh-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon2161-21292150-751110.1128/mBio.03656-20https://doaj.org/article/985188f48aa746a1a0c85edf7d900fa12021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03656-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Achieving strain-level resolution is a major obstacle for source tracking and temporal studies of microbiomes. In this study, we describe a novel deep-sequencing approach that provides species- and strain-level resolution of the neonatal microbiome.J. GrafN. LedalaM. J. CaimanoE. JacksonD. GrataloD. FasuloM. D. DriscollS. ColemanA. P. MatsonAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
J. Graf
N. Ledala
M. J. Caimano
E. Jackson
D. Gratalo
D. Fasulo
M. D. Driscoll
S. Coleman
A. P. Matson
High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon
description Achieving strain-level resolution is a major obstacle for source tracking and temporal studies of microbiomes. In this study, we describe a novel deep-sequencing approach that provides species- and strain-level resolution of the neonatal microbiome.
format article
author J. Graf
N. Ledala
M. J. Caimano
E. Jackson
D. Gratalo
D. Fasulo
M. D. Driscoll
S. Coleman
A. P. Matson
author_facet J. Graf
N. Ledala
M. J. Caimano
E. Jackson
D. Gratalo
D. Fasulo
M. D. Driscoll
S. Coleman
A. P. Matson
author_sort J. Graf
title High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon
title_short High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon
title_full High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon
title_fullStr High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon
title_full_unstemmed High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon
title_sort high-resolution differentiation of enteric bacteria in premature infant fecal microbiomes using a novel rrna amplicon
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/985188f48aa746a1a0c85edf7d900fa1
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