Absence of AKT1 mutations in glioblastoma.
<h4>Background</h4>Oncogenic activation of the PI3K signalling pathway plays a pivotal role in the development of glioblastoma multiforme (GBM). A central node in PI3K downstream signalling is controlled by the serine-threonine kinase AKT1. A somatic mutation affecting residue E17 of the...
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| Main Authors: | , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2009
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| Subjects: | |
| Online Access: | https://doaj.org/article/9852c5c98a3b47aa91e3f8d3b920641e |
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