Metabolic syndrome in adults with a history of juvenile arthritis

Sangeeta Sule,1 Kevin Fontaine2 1Department of Pediatric, Pediatric Rheumatology, Johns Hopkins University, Baltimore, MD, USA; 2Department of Health Behavior, University of Alabama at Birmingham, Birmingham, AL, USA Objective: The objective of this study was to determine the risk of obesity and met...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sule S, Fontaine K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Juvenile idiopathic arthritis outcomes research cardiovascular disease Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/985415c1fb9548e28adff7aea9a062af
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:985415c1fb9548e28adff7aea9a062af
record_format	dspace
spelling	oai:doaj.org-article:985415c1fb9548e28adff7aea9a062af2021-12-02T07:59:43ZMetabolic syndrome in adults with a history of juvenile arthritis1179-156Xhttps://doaj.org/article/985415c1fb9548e28adff7aea9a062af2018-06-01T00:00:00Zhttps://www.dovepress.com/metabolic-syndrome-in-adults-with-a-history-of-juvenile-arthritis-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XSangeeta Sule,1 Kevin Fontaine2 1Department of Pediatric, Pediatric Rheumatology, Johns Hopkins University, Baltimore, MD, USA; 2Department of Health Behavior, University of Alabama at Birmingham, Birmingham, AL, USA Objective: The objective of this study was to determine the risk of obesity and metabolic syndrome in adults with a history of juvenile arthritis (JA). Methods: Using the National Health and Nutrition Examination Survey (NHANES), we compared the characteristics of respondents with arthritis (JA vs rheumatoid arthritis [RA]) to those of the control group without arthritis. We used logistic regression analyses, controlling for age, race, and gender, to determine the ORs for metabolic syndrome. Results: Obesity was increased in the JA group with 67% respondents having body mass index ≥30 kg/m2 vs 55% respondents in the no arthritis cohort (p=0.004). In unadjusted analyses, there was increased odds of metabolic syndrome in JA (OR 6.2, p=0.001) and RA groups compared to those without arthritis (OR 7.7, p=0.001). After adjusting for age, gender, and race, the odds of metabolic syndrome remained increased in JA (OR 5.2, p=0.001) and RA (OR 3.2, p=0.001) groups. Conclusion: Adults with a history of JA have a significantly increased risk of metabolic syndrome compared to those without arthritis. These findings are important because metabolic syndrome has been associated with an increased risk of cardiovascular disease and death in other populations. Keywords: juvenile arthritis, outcomes research, cardiovascular diseaseSule SFontaine KDove Medical PressarticleJuvenile idiopathic arthritisoutcomes researchcardiovascular diseaseDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 10, Pp 67-72 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Juvenile idiopathic arthritis outcomes research cardiovascular disease Diseases of the musculoskeletal system RC925-935
spellingShingle	Juvenile idiopathic arthritis outcomes research cardiovascular disease Diseases of the musculoskeletal system RC925-935 Sule S Fontaine K Metabolic syndrome in adults with a history of juvenile arthritis
description	Sangeeta Sule,1 Kevin Fontaine2 1Department of Pediatric, Pediatric Rheumatology, Johns Hopkins University, Baltimore, MD, USA; 2Department of Health Behavior, University of Alabama at Birmingham, Birmingham, AL, USA Objective: The objective of this study was to determine the risk of obesity and metabolic syndrome in adults with a history of juvenile arthritis (JA). Methods: Using the National Health and Nutrition Examination Survey (NHANES), we compared the characteristics of respondents with arthritis (JA vs rheumatoid arthritis [RA]) to those of the control group without arthritis. We used logistic regression analyses, controlling for age, race, and gender, to determine the ORs for metabolic syndrome. Results: Obesity was increased in the JA group with 67% respondents having body mass index ≥30 kg/m2 vs 55% respondents in the no arthritis cohort (p=0.004). In unadjusted analyses, there was increased odds of metabolic syndrome in JA (OR 6.2, p=0.001) and RA groups compared to those without arthritis (OR 7.7, p=0.001). After adjusting for age, gender, and race, the odds of metabolic syndrome remained increased in JA (OR 5.2, p=0.001) and RA (OR 3.2, p=0.001) groups. Conclusion: Adults with a history of JA have a significantly increased risk of metabolic syndrome compared to those without arthritis. These findings are important because metabolic syndrome has been associated with an increased risk of cardiovascular disease and death in other populations. Keywords: juvenile arthritis, outcomes research, cardiovascular disease
format	article
author	Sule S Fontaine K
author_facet	Sule S Fontaine K
author_sort	Sule S
title	Metabolic syndrome in adults with a history of juvenile arthritis
title_short	Metabolic syndrome in adults with a history of juvenile arthritis
title_full	Metabolic syndrome in adults with a history of juvenile arthritis
title_fullStr	Metabolic syndrome in adults with a history of juvenile arthritis
title_full_unstemmed	Metabolic syndrome in adults with a history of juvenile arthritis
title_sort	metabolic syndrome in adults with a history of juvenile arthritis
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/985415c1fb9548e28adff7aea9a062af
work_keys_str_mv	AT sules metabolicsyndromeinadultswithahistoryofjuvenilearthritis AT fontainek metabolicsyndromeinadultswithahistoryofjuvenilearthritis
_version_	1718398737631412224

Metabolic syndrome in adults with a history of juvenile arthritis

Ejemplares similares