Epilepsy and suicide: pathogenesis, risk factors, and prevention

Alberto Verrotti1, Alessandra Cicconetti2, Barbara Scorrano2, Domenico De Berardis2,3, Carla Cotellessa2, Francesco Chiarelli1, Filippo Maria Ferro21Department of Pediatrics; 2Department of Oncology and Neuroscience, Institute of Psychiatry, University &ldquo;G. d&rsquo;Annunzio&...

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Autores principales:	Alberto Verrotti, Alessandra Cicconetti, Barbara Scorrano, Domenico De Berardis, Carla Cotellessa, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/9854f626869d49bb822666da145c1fa4
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spelling	oai:doaj.org-article:9854f626869d49bb822666da145c1fa42021-12-02T02:04:03ZEpilepsy and suicide: pathogenesis, risk factors, and prevention1176-63281178-2021https://doaj.org/article/9854f626869d49bb822666da145c1fa42008-04-01T00:00:00Zhttp://www.dovepress.com/epilepsy-and-suicide-pathogenesis-risk-factors-and-prevention-a1035https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Alberto Verrotti1, Alessandra Cicconetti2, Barbara Scorrano2, Domenico De Berardis2,3, Carla Cotellessa2, Francesco Chiarelli1, Filippo Maria Ferro21Department of Pediatrics; 2Department of Oncology and Neuroscience, Institute of Psychiatry, University &ldquo;G. d&rsquo;Annunzio&rdquo; of Chieti, Italy; 3Department of Mental Health, Teramo, ItalyAbstract: Depression and suicide tendencies are common in chronic diseases, especially in epilepsy and diabetes. Suicide is one of the most important causes of death, and is usually underestimated. We have analyzed several studies that compare mortality as a result of suicide in epileptic patients and in the general population. All the studies show that epileptic patients have a stronger tendency toward suicide than healthy controls. Moreover it seems that some kinds of epilepsy have a higher risk for suicide (temporal-lobe epilepsy). Among the risk factors are surgery therapy (suicide tendency five times higher than patients in pharmacological therapy), absence of seizures for a long time, especially after being very frequent, and psychiatric comorbidity (major depression, anxiety-depression disorders, personality disorders, substance abuse, psychoses). The aim of the review was to analyze the relationship between suicide and epilepsy, to identify the major risk factors, and to analyze effective treatment options.Keywords: epilepsy, suicide, depression Alberto VerrottiAlessandra CicconettiBarbara ScorranoDomenico De BerardisCarla Cotellessaet alDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 2, Pp 365-370 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Alberto Verrotti Alessandra Cicconetti Barbara Scorrano Domenico De Berardis Carla Cotellessa et al Epilepsy and suicide: pathogenesis, risk factors, and prevention
description	Alberto Verrotti1, Alessandra Cicconetti2, Barbara Scorrano2, Domenico De Berardis2,3, Carla Cotellessa2, Francesco Chiarelli1, Filippo Maria Ferro21Department of Pediatrics; 2Department of Oncology and Neuroscience, Institute of Psychiatry, University &ldquo;G. d&rsquo;Annunzio&rdquo; of Chieti, Italy; 3Department of Mental Health, Teramo, ItalyAbstract: Depression and suicide tendencies are common in chronic diseases, especially in epilepsy and diabetes. Suicide is one of the most important causes of death, and is usually underestimated. We have analyzed several studies that compare mortality as a result of suicide in epileptic patients and in the general population. All the studies show that epileptic patients have a stronger tendency toward suicide than healthy controls. Moreover it seems that some kinds of epilepsy have a higher risk for suicide (temporal-lobe epilepsy). Among the risk factors are surgery therapy (suicide tendency five times higher than patients in pharmacological therapy), absence of seizures for a long time, especially after being very frequent, and psychiatric comorbidity (major depression, anxiety-depression disorders, personality disorders, substance abuse, psychoses). The aim of the review was to analyze the relationship between suicide and epilepsy, to identify the major risk factors, and to analyze effective treatment options.Keywords: epilepsy, suicide, depression
format	article
author	Alberto Verrotti Alessandra Cicconetti Barbara Scorrano Domenico De Berardis Carla Cotellessa et al
author_facet	Alberto Verrotti Alessandra Cicconetti Barbara Scorrano Domenico De Berardis Carla Cotellessa et al
author_sort	Alberto Verrotti
title	Epilepsy and suicide: pathogenesis, risk factors, and prevention
title_short	Epilepsy and suicide: pathogenesis, risk factors, and prevention
title_full	Epilepsy and suicide: pathogenesis, risk factors, and prevention
title_fullStr	Epilepsy and suicide: pathogenesis, risk factors, and prevention
title_full_unstemmed	Epilepsy and suicide: pathogenesis, risk factors, and prevention
title_sort	epilepsy and suicide: pathogenesis, risk factors, and prevention
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/9854f626869d49bb822666da145c1fa4
work_keys_str_mv	AT albertoverrotti epilepsyandsuicidepathogenesisriskfactorsandprevention AT alessandracicconetti epilepsyandsuicidepathogenesisriskfactorsandprevention AT barbarascorrano epilepsyandsuicidepathogenesisriskfactorsandprevention AT domenicodeberardis epilepsyandsuicidepathogenesisriskfactorsandprevention AT carlacotellessa epilepsyandsuicidepathogenesisriskfactorsandprevention AT etal epilepsyandsuicidepathogenesisriskfactorsandprevention
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Epilepsy and suicide: pathogenesis, risk factors, and prevention

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