Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs

Kaori Hirai1,4, Yoji Takano2, Eiichi Uchio3, Kazuaki Kadonosono41Department of Ophthalmology, International Goodwill Hospital, 2Department of Ophthalmology, Kitasato Institute Hospital, 3Department of Ophthalmology, Fukuoka, Fukuoka, Japan; 4Department of Ophthalmology, Yokohama City University Medi...

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Autores principales:	Kadonosono K, Uchio E, Takano Y, Hirai K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9855d08f7f0545f8a0a0f1b5b67b54f5
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spelling	oai:doaj.org-article:9855d08f7f0545f8a0a0f1b5b67b54f52021-12-02T07:14:42ZClinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs1177-54671177-5483https://doaj.org/article/9855d08f7f0545f8a0a0f1b5b67b54f52012-01-01T00:00:00Zhttp://www.dovepress.com/clinical-evaluation-of-the-therapeutic-effects-of-atelocollagen-absorb-a9072https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kaori Hirai1,4, Yoji Takano2, Eiichi Uchio3, Kazuaki Kadonosono41Department of Ophthalmology, International Goodwill Hospital, 2Department of Ophthalmology, Kitasato Institute Hospital, 3Department of Ophthalmology, Fukuoka, Fukuoka, Japan; 4Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, JapanPurpose: To evaluate the therapeutic effects of atelocollagen absorbable punctal plugs.Method: Seventy-four eyes in 37 patients with dry eye disease (DED) underwent punctal plug occlusion using atelocollagen plugs and were followed up for 24 weeks. Subjective symptoms were evaluated using the ocular surface disease index (OSDI) questionnaire. Ocular surface disease parameters, including the Schirmer test, phenol red thread test, tear break-up time (TBUT), and fluorescein and Rose Bengal staining, were recorded before and 1, 4, 8, 16, and 24 weeks after treatment.Results: In comparison with the pretreatment data, the subjective symptoms and ocular surface disease parameters showed significant improvement after atelocollagen punctal occlusion. The average time of relapse was 17.4 &plusmn; 5.1 weeks. No severe complications occurred, and none of the plugs had to be removed because of local discomfort or epiphora.Conclusion: Atelocollagen absorbable punctal plugs effectively improved ocular surface disorders in DED. These plugs are a safe and effective alternative in the treatment of DED.Keywords: atelocollagen, absorbable punctual plug, dry eyeKadonosono KUchio ETakano YHirai KDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 133-138 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kadonosono K Uchio E Takano Y Hirai K Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
description	Kaori Hirai1,4, Yoji Takano2, Eiichi Uchio3, Kazuaki Kadonosono41Department of Ophthalmology, International Goodwill Hospital, 2Department of Ophthalmology, Kitasato Institute Hospital, 3Department of Ophthalmology, Fukuoka, Fukuoka, Japan; 4Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, JapanPurpose: To evaluate the therapeutic effects of atelocollagen absorbable punctal plugs.Method: Seventy-four eyes in 37 patients with dry eye disease (DED) underwent punctal plug occlusion using atelocollagen plugs and were followed up for 24 weeks. Subjective symptoms were evaluated using the ocular surface disease index (OSDI) questionnaire. Ocular surface disease parameters, including the Schirmer test, phenol red thread test, tear break-up time (TBUT), and fluorescein and Rose Bengal staining, were recorded before and 1, 4, 8, 16, and 24 weeks after treatment.Results: In comparison with the pretreatment data, the subjective symptoms and ocular surface disease parameters showed significant improvement after atelocollagen punctal occlusion. The average time of relapse was 17.4 &plusmn; 5.1 weeks. No severe complications occurred, and none of the plugs had to be removed because of local discomfort or epiphora.Conclusion: Atelocollagen absorbable punctal plugs effectively improved ocular surface disorders in DED. These plugs are a safe and effective alternative in the treatment of DED.Keywords: atelocollagen, absorbable punctual plug, dry eye
format	article
author	Kadonosono K Uchio E Takano Y Hirai K
author_facet	Kadonosono K Uchio E Takano Y Hirai K
author_sort	Kadonosono K
title	Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
title_short	Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
title_full	Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
title_fullStr	Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
title_full_unstemmed	Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
title_sort	clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/9855d08f7f0545f8a0a0f1b5b67b54f5
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Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs

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