Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters

Single cells can display large heterogeneity in gene induction. Here, Aymoz et al. present an expression reporter based on protein translocation that can accurately measure both the levels and dynamics of protein synthesis in live single cells with a temporal resolution of less than one minute.

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Detalles Bibliográficos
Autores principales:	Delphine Aymoz, Victoria Wosika, Eric Durandau, Serge Pelet
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/985c22e4d7a44ff48c0c5e471df76961
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spelling	oai:doaj.org-article:985c22e4d7a44ff48c0c5e471df769612021-12-02T14:39:49ZReal-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters10.1038/ncomms113042041-1723https://doaj.org/article/985c22e4d7a44ff48c0c5e471df769612016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11304https://doaj.org/toc/2041-1723Single cells can display large heterogeneity in gene induction. Here, Aymoz et al. present an expression reporter based on protein translocation that can accurately measure both the levels and dynamics of protein synthesis in live single cells with a temporal resolution of less than one minute.Delphine AymozVictoria WosikaEric DurandauSerge PeletNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Delphine Aymoz Victoria Wosika Eric Durandau Serge Pelet Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters
description	Single cells can display large heterogeneity in gene induction. Here, Aymoz et al. present an expression reporter based on protein translocation that can accurately measure both the levels and dynamics of protein synthesis in live single cells with a temporal resolution of less than one minute.
format	article
author	Delphine Aymoz Victoria Wosika Eric Durandau Serge Pelet
author_facet	Delphine Aymoz Victoria Wosika Eric Durandau Serge Pelet
author_sort	Delphine Aymoz
title	Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters
title_short	Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters
title_full	Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters
title_fullStr	Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters
title_full_unstemmed	Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters
title_sort	real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/985c22e4d7a44ff48c0c5e471df76961
work_keys_str_mv	AT delphineaymoz realtimequantificationofproteinexpressionatthesinglecelllevelviadynamicproteinsynthesistranslocationreporters AT victoriawosika realtimequantificationofproteinexpressionatthesinglecelllevelviadynamicproteinsynthesistranslocationreporters AT ericdurandau realtimequantificationofproteinexpressionatthesinglecelllevelviadynamicproteinsynthesistranslocationreporters AT sergepelet realtimequantificationofproteinexpressionatthesinglecelllevelviadynamicproteinsynthesistranslocationreporters
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Real-time quantification of protein expression at the single-cell level via dynamic protein synthesis translocation reporters

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