Lincomycin biosynthesis involves a tyrosine hydroxylating heme protein of an unusual enzyme family.

The gene lmbB2 of the lincomycin biosynthetic gene cluster of Streptomyces lincolnensis ATCC 25466 was shown to code for an unusual tyrosine hydroxylating enzyme involved in the biosynthetic pathway of this clinically important antibiotic. LmbB2 was expressed in Escherichia coli, purified near to ho...

Full description

Saved in:
Bibliographic Details
Main Authors: Jitka Novotna, Jana Olsovska, Petr Novak, Peter Mojzes, Radka Chaloupkova, Zdenek Kamenik, Jaroslav Spizek, Eva Kutejova, Marketa Mareckova, Pavel Tichy, Jiri Damborsky, Jiri Janata
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/985c474f95164d1dbd6ad0c2af5718a4
Tags: Add Tag
No Tags, Be the first to tag this record!