Genetically-determined hyperfunction of the S100B/RAGE axis is a risk factor for aspergillosis in stem cell transplant recipients.

Genetically-determined hyperfunction of the S100B/RAGE axis is a risk factor for aspergillosis in stem cell transplant recipients.

Invasive aspergillosis (IA) is a major threat to the successful outcome of hematopoietic stem cell transplantation (HSCT), although individual risk varies considerably. Recent evidence has established a pivotal role for a danger sensing mechanism implicating the S100B/receptor for advanced glycation...

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Autores principales: Cristina Cunha, Gloria Giovannini, Antonio Pierini, Alain S Bell, Guglielmo Sorci, Francesca Riuzzi, Rosario Donato, Fernando Rodrigues, Andrea Velardi, Franco Aversa, Luigina Romani, Agostinho Carvalho
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/985cef9f6e544e378f08b8bcde2228c8
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