Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital

Background/Purpose The high prevalence of hypovitaminosis D among trauma patients have been related to risk of fractures, falls, non-union and poor operative outcomes. There is limited evidence that ties up Vitamin D levels with fracture severity. The objective of this study is to determine the asso...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Christian Julius P. Mendoza MD, DPBO, Mikhail Lew Perez Ver MD, FPOA, Andrew Gabriel Jacinto Tabberrah MD, FPOA, Mario Ratio Ver MD, FPOA
Format:	article
Langue:	EN
Publié:	SAGE Publishing 2021
Sujets:	Orthopedic surgery RD701-811
Accès en ligne:	https://doaj.org/article/9865541e1adf42229ddb6a8b4f5ea4ab
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

id	oai:doaj.org-article:9865541e1adf42229ddb6a8b4f5ea4ab
record_format	dspace
spelling	oai:doaj.org-article:9865541e1adf42229ddb6a8b4f5ea4ab2021-12-03T23:03:30ZAssociation of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital2210-492510.1177/22104917211056942https://doaj.org/article/9865541e1adf42229ddb6a8b4f5ea4ab2021-12-01T00:00:00Zhttps://doi.org/10.1177/22104917211056942https://doaj.org/toc/2210-4925Background/Purpose The high prevalence of hypovitaminosis D among trauma patients have been related to risk of fractures, falls, non-union and poor operative outcomes. There is limited evidence that ties up Vitamin D levels with fracture severity. The objective of this study is to determine the association of pre-operative Vitamin D levels and fracture severity. Methods This was a retrospective, cross-sectional study of patients with extremity fractures classified according to the AO Trauma classification system with baseline pre-operative vitamin D levels. The association between vitamin D levels and fracture severity of surgically treated trauma patients were analyzed. Sub-group analysis was performed on patients without osteoporosis and those patients who suffered from low-energy trauma. Results Ninety-six (96) patients were included. Those with severe fractures (AO -C fractures, 31B1.3/B2.3 and 31A3) were associated with lower Vitamin D levels (µ = 17.87 µg/mL) (p < 0.001). There was a strong, positive significant correlation ( r s (4) = .426, p = < 0.001) between hypovitaminosis D and increasing fracture severity. This significant association of hypovitaminosis D with worse fracture patterns remains in the patient sub-group without osteoporosis ( p = 0.030), and in those who sustained low-mechanism injuries ( p < 0.001). Conclusion We present initial evidence that low pre-operative Vitamin D level is associated with increasing fracture severity at the time of injury. Early detection, surveillance and management of low vitamin D levels can lead to drastic changes in the holistic approach to fracture prevention and treatment.Christian Julius P. Mendoza MD, DPBOMikhail Lew Perez Ver MD, FPOAAndrew Gabriel Jacinto Tabberrah MD, FPOAMario Ratio Ver MD, FPOASAGE PublishingarticleOrthopedic surgeryRD701-811ENJournal of Orthopaedics, Trauma and Rehabilitation, Vol 28 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Orthopedic surgery RD701-811
spellingShingle	Orthopedic surgery RD701-811 Christian Julius P. Mendoza MD, DPBO Mikhail Lew Perez Ver MD, FPOA Andrew Gabriel Jacinto Tabberrah MD, FPOA Mario Ratio Ver MD, FPOA Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital
description	Background/Purpose The high prevalence of hypovitaminosis D among trauma patients have been related to risk of fractures, falls, non-union and poor operative outcomes. There is limited evidence that ties up Vitamin D levels with fracture severity. The objective of this study is to determine the association of pre-operative Vitamin D levels and fracture severity. Methods This was a retrospective, cross-sectional study of patients with extremity fractures classified according to the AO Trauma classification system with baseline pre-operative vitamin D levels. The association between vitamin D levels and fracture severity of surgically treated trauma patients were analyzed. Sub-group analysis was performed on patients without osteoporosis and those patients who suffered from low-energy trauma. Results Ninety-six (96) patients were included. Those with severe fractures (AO -C fractures, 31B1.3/B2.3 and 31A3) were associated with lower Vitamin D levels (µ = 17.87 µg/mL) (p < 0.001). There was a strong, positive significant correlation ( r s (4) = .426, p = < 0.001) between hypovitaminosis D and increasing fracture severity. This significant association of hypovitaminosis D with worse fracture patterns remains in the patient sub-group without osteoporosis ( p = 0.030), and in those who sustained low-mechanism injuries ( p < 0.001). Conclusion We present initial evidence that low pre-operative Vitamin D level is associated with increasing fracture severity at the time of injury. Early detection, surveillance and management of low vitamin D levels can lead to drastic changes in the holistic approach to fracture prevention and treatment.
format	article
author	Christian Julius P. Mendoza MD, DPBO Mikhail Lew Perez Ver MD, FPOA Andrew Gabriel Jacinto Tabberrah MD, FPOA Mario Ratio Ver MD, FPOA
author_facet	Christian Julius P. Mendoza MD, DPBO Mikhail Lew Perez Ver MD, FPOA Andrew Gabriel Jacinto Tabberrah MD, FPOA Mario Ratio Ver MD, FPOA
author_sort	Christian Julius P. Mendoza MD, DPBO
title	Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital
title_short	Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital
title_full	Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital
title_fullStr	Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital
title_full_unstemmed	Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital
title_sort	association of pre-operative vitamin d levels and severity of fracture among orthopedic trauma patients in a single, tertiary-level hospital
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/9865541e1adf42229ddb6a8b4f5ea4ab
work_keys_str_mv	AT christianjuliuspmendozamddpbo associationofpreoperativevitamindlevelsandseverityoffractureamongorthopedictraumapatientsinasingletertiarylevelhospital AT mikhaillewperezvermdfpoa associationofpreoperativevitamindlevelsandseverityoffractureamongorthopedictraumapatientsinasingletertiarylevelhospital AT andrewgabrieljacintotabberrahmdfpoa associationofpreoperativevitamindlevelsandseverityoffractureamongorthopedictraumapatientsinasingletertiarylevelhospital AT marioratiovermdfpoa associationofpreoperativevitamindlevelsandseverityoffractureamongorthopedictraumapatientsinasingletertiarylevelhospital
_version_	1718373089095450624

Association of Pre-Operative Vitamin D Levels and Severity of Fracture among Orthopedic Trauma Patients in A Single, Tertiary-Level Hospital

Documents similaires