Discovering the Potent Inhibitors Against Babesia bovis in vitro and Babesia microti in vivo by Repurposing the Natural Product Compounds

Discovering the Potent Inhibitors Against Babesia bovis in vitro and Babesia microti in vivo by Repurposing the Natural Product Compounds

In the present study, we screened 502 natural product compounds against the in vitro growth of Babesia (B.) bovis. Then, the novel and potent identified compounds were further evaluated for their in vitro efficacies using viability and cytotoxicity assays. The in vivo inhibitory effects of the selec...

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Bibliographic Details
Main Authors: Yongchang Li, Mohamed Abdo Rizk, Eloiza May Galon, Mingming Liu, Jixu Li, Aaron Edmond Ringo, Shengwei Ji, Iqra Zafar, Maria Agnes Tumwebaze, Byamukama Benedicto, Naoaki Yokoyama, Ikuo Igarashi, Bayin Chahan, Xuenan Xuan
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
natural product compounds
Babesia bovis
in vitro
Babesia microti
in vivo
Veterinary medicine
SF600-1100
Online Access:https://doaj.org/article/986906b003574c5ca593d357711b9414
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https://doaj.org/article/986906b003574c5ca593d357711b9414

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