Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy

Brett E Youngerman, Farhan A Khan, Guy M McKhannDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USAAbstract: For patients with drug-resistant epilepsy, surgical intervention may be an effective treatment option if the epileptogenic zone (EZ) can be well localize...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Youngerman BE, Khan FA, McKhann GM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Stereoelectroencephalography SEEG epilepsy surgery cognitive neurophysiology psychiatric neurosurgery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/9875e2353eff41c9b425c3ad9a358867
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9875e2353eff41c9b425c3ad9a358867
record_format	dspace
spelling	oai:doaj.org-article:9875e2353eff41c9b425c3ad9a3588672021-12-02T06:24:35ZStereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy1178-2021https://doaj.org/article/9875e2353eff41c9b425c3ad9a3588672019-06-01T00:00:00Zhttps://www.dovepress.com/stereoelectroencephalography-in-epilepsy-cognitive-neurophysiology-and-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Brett E Youngerman, Farhan A Khan, Guy M McKhannDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USAAbstract: For patients with drug-resistant epilepsy, surgical intervention may be an effective treatment option if the epileptogenic zone (EZ) can be well localized. Subdural strip and grid electrode (SDE) implantations have long been used as the mainstay of intracranial seizure localization in the United States. Stereoelectroencephalography (SEEG) is an alternative approach in which depth electrodes are placed through percutaneous drill holes to stereotactically defined coordinates in the brain. Long used in certain centers in Europe, SEEG is gaining wider popularity in North America, bolstered by the advent of stereotactic robotic assistance and mounting evidence of safety, without the need for catheter-based angiography. Rates of clinically significant hemorrhage, infection, and other complications appear lower with SEEG than with SDE implants. SEEG also avoids unnecessary craniotomies when seizures are localized to unresectable eloquent cortex, found to be multifocal or nonfocal, or ultimately treated with stereotactic procedures such as laser interstitial thermal therapy (LITT), radiofrequency thermocoagulation (RF-TC), responsive neurostimulation (RNS), or deep brain stimulation (DBS). While SDE allows for excellent localization and functional mapping on the cortical surface, SEEG offers a less invasive option for sampling disparate brain areas, bilateral investigations, and deep or medial targets. SEEG has shown efficacy for seizure localization in the temporal lobe, the insula, lesional and nonlesional extra-temporal epilepsy, hypothalamic hamartomas, periventricular nodular heterotopias, and patients who have had prior craniotomies for resections or grids. SEEG offers a valuable opportunity for cognitive neurophysiology research and may have an important role in the study of dysfunctional networks in psychiatric disease and understanding the effects of neuromodulation.Keywords: stereoelectroencephalography, SEEG, epilepsy surgery, cognitive neurophysiology, psychiatric neurosurgeryYoungerman BEKhan FAMcKhann GMDove Medical PressarticleStereoelectroencephalographySEEGepilepsy surgerycognitive neurophysiologypsychiatric neurosurgeryNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 15, Pp 1701-1716 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Stereoelectroencephalography SEEG epilepsy surgery cognitive neurophysiology psychiatric neurosurgery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Stereoelectroencephalography SEEG epilepsy surgery cognitive neurophysiology psychiatric neurosurgery Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Youngerman BE Khan FA McKhann GM Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy
description	Brett E Youngerman, Farhan A Khan, Guy M McKhannDepartment of Neurological Surgery, Columbia University Medical Center, New York, NY, USAAbstract: For patients with drug-resistant epilepsy, surgical intervention may be an effective treatment option if the epileptogenic zone (EZ) can be well localized. Subdural strip and grid electrode (SDE) implantations have long been used as the mainstay of intracranial seizure localization in the United States. Stereoelectroencephalography (SEEG) is an alternative approach in which depth electrodes are placed through percutaneous drill holes to stereotactically defined coordinates in the brain. Long used in certain centers in Europe, SEEG is gaining wider popularity in North America, bolstered by the advent of stereotactic robotic assistance and mounting evidence of safety, without the need for catheter-based angiography. Rates of clinically significant hemorrhage, infection, and other complications appear lower with SEEG than with SDE implants. SEEG also avoids unnecessary craniotomies when seizures are localized to unresectable eloquent cortex, found to be multifocal or nonfocal, or ultimately treated with stereotactic procedures such as laser interstitial thermal therapy (LITT), radiofrequency thermocoagulation (RF-TC), responsive neurostimulation (RNS), or deep brain stimulation (DBS). While SDE allows for excellent localization and functional mapping on the cortical surface, SEEG offers a less invasive option for sampling disparate brain areas, bilateral investigations, and deep or medial targets. SEEG has shown efficacy for seizure localization in the temporal lobe, the insula, lesional and nonlesional extra-temporal epilepsy, hypothalamic hamartomas, periventricular nodular heterotopias, and patients who have had prior craniotomies for resections or grids. SEEG offers a valuable opportunity for cognitive neurophysiology research and may have an important role in the study of dysfunctional networks in psychiatric disease and understanding the effects of neuromodulation.Keywords: stereoelectroencephalography, SEEG, epilepsy surgery, cognitive neurophysiology, psychiatric neurosurgery
format	article
author	Youngerman BE Khan FA McKhann GM
author_facet	Youngerman BE Khan FA McKhann GM
author_sort	Youngerman BE
title	Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy
title_short	Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy
title_full	Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy
title_fullStr	Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy
title_full_unstemmed	Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy
title_sort	stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/9875e2353eff41c9b425c3ad9a358867
work_keys_str_mv	AT youngermanbe stereoelectroencephalographyinepilepsycognitiveneurophysiologyandpsychiatricdiseasesafetyefficacyandplaceintherapy AT khanfa stereoelectroencephalographyinepilepsycognitiveneurophysiologyandpsychiatricdiseasesafetyefficacyandplaceintherapy AT mckhanngm stereoelectroencephalographyinepilepsycognitiveneurophysiologyandpsychiatricdiseasesafetyefficacyandplaceintherapy
_version_	1718399951424192512

Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy

Ejemplares similares