The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers

SWI/SNF chromatin remodelling complex is a major regulator of chromatin structure and of transcription. Here, using mouse embryonic fibroblasts and human rhabdoid tumour cells, the authors provide evidence that SWI/SNF functions as a regulator of enhancers.

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Autores principales: Burak H. Alver, Kimberly H. Kim, Ping Lu, Xiaofeng Wang, Haley E. Manchester, Weishan Wang, Jeffrey R. Haswell, Peter J. Park, Charles W. M. Roberts
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/987848cfa7004d11b8b1c3154bd8c459
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spelling oai:doaj.org-article:987848cfa7004d11b8b1c3154bd8c4592021-12-02T14:42:22ZThe SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers10.1038/ncomms146482041-1723https://doaj.org/article/987848cfa7004d11b8b1c3154bd8c4592017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14648https://doaj.org/toc/2041-1723SWI/SNF chromatin remodelling complex is a major regulator of chromatin structure and of transcription. Here, using mouse embryonic fibroblasts and human rhabdoid tumour cells, the authors provide evidence that SWI/SNF functions as a regulator of enhancers.Burak H. AlverKimberly H. KimPing LuXiaofeng WangHaley E. ManchesterWeishan WangJeffrey R. HaswellPeter J. ParkCharles W. M. RobertsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Burak H. Alver
Kimberly H. Kim
Ping Lu
Xiaofeng Wang
Haley E. Manchester
Weishan Wang
Jeffrey R. Haswell
Peter J. Park
Charles W. M. Roberts
The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
description SWI/SNF chromatin remodelling complex is a major regulator of chromatin structure and of transcription. Here, using mouse embryonic fibroblasts and human rhabdoid tumour cells, the authors provide evidence that SWI/SNF functions as a regulator of enhancers.
format article
author Burak H. Alver
Kimberly H. Kim
Ping Lu
Xiaofeng Wang
Haley E. Manchester
Weishan Wang
Jeffrey R. Haswell
Peter J. Park
Charles W. M. Roberts
author_facet Burak H. Alver
Kimberly H. Kim
Ping Lu
Xiaofeng Wang
Haley E. Manchester
Weishan Wang
Jeffrey R. Haswell
Peter J. Park
Charles W. M. Roberts
author_sort Burak H. Alver
title The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
title_short The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
title_full The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
title_fullStr The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
title_full_unstemmed The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
title_sort swi/snf chromatin remodelling complex is required for maintenance of lineage specific enhancers
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/987848cfa7004d11b8b1c3154bd8c459
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