Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity

Circuits of the preBötzinger complex generate rhythms needed for breathing. Here, the authors provide evidence, using a combination of chemogenetic approaches and approaches to inhibit vesicular release, that astrocytes play a role in regulating respiratory rate.

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Autores principales:	Shahriar Sheikhbahaei, Egor A. Turovsky, Patrick S. Hosford, Anna Hadjihambi, Shefeeq M. Theparambil, Beihui Liu, Nephtali Marina, Anja G. Teschemacher, Sergey Kasparov, Jeffrey C. Smith, Alexander V. Gourine
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/988bcc66305d4c098978f289c873fba5
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spelling	oai:doaj.org-article:988bcc66305d4c098978f289c873fba52021-12-02T14:38:48ZAstrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity10.1038/s41467-017-02723-62041-1723https://doaj.org/article/988bcc66305d4c098978f289c873fba52018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02723-6https://doaj.org/toc/2041-1723Circuits of the preBötzinger complex generate rhythms needed for breathing. Here, the authors provide evidence, using a combination of chemogenetic approaches and approaches to inhibit vesicular release, that astrocytes play a role in regulating respiratory rate.Shahriar SheikhbahaeiEgor A. TurovskyPatrick S. HosfordAnna HadjihambiShefeeq M. TheparambilBeihui LiuNephtali MarinaAnja G. TeschemacherSergey KasparovJeffrey C. SmithAlexander V. GourineNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shahriar Sheikhbahaei Egor A. Turovsky Patrick S. Hosford Anna Hadjihambi Shefeeq M. Theparambil Beihui Liu Nephtali Marina Anja G. Teschemacher Sergey Kasparov Jeffrey C. Smith Alexander V. Gourine Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
description	Circuits of the preBötzinger complex generate rhythms needed for breathing. Here, the authors provide evidence, using a combination of chemogenetic approaches and approaches to inhibit vesicular release, that astrocytes play a role in regulating respiratory rate.
format	article
author	Shahriar Sheikhbahaei Egor A. Turovsky Patrick S. Hosford Anna Hadjihambi Shefeeq M. Theparambil Beihui Liu Nephtali Marina Anja G. Teschemacher Sergey Kasparov Jeffrey C. Smith Alexander V. Gourine
author_facet	Shahriar Sheikhbahaei Egor A. Turovsky Patrick S. Hosford Anna Hadjihambi Shefeeq M. Theparambil Beihui Liu Nephtali Marina Anja G. Teschemacher Sergey Kasparov Jeffrey C. Smith Alexander V. Gourine
author_sort	Shahriar Sheikhbahaei
title	Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
title_short	Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
title_full	Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
title_fullStr	Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
title_full_unstemmed	Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
title_sort	astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/988bcc66305d4c098978f289c873fba5
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Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity

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