Assessing suicidal risk with antiepileptic drugs

Marco Mula2, Gail S Bell1, Josemir W Sander1,31Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom; 2Department of Clinical and Experimental Medicine, Division o...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Marco Mula, Gail S Bell, Josemir W Sander
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://doaj.org/article/98914a0b680d4ade83e1ffc2b73a0848
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:98914a0b680d4ade83e1ffc2b73a0848
record_format dspace
spelling oai:doaj.org-article:98914a0b680d4ade83e1ffc2b73a08482021-12-02T05:15:24ZAssessing suicidal risk with antiepileptic drugs1176-63281178-2021https://doaj.org/article/98914a0b680d4ade83e1ffc2b73a08482010-09-01T00:00:00Zhttp://www.dovepress.com/assessing-suicidal-risk-with-antiepileptic-drugs-a5270https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Marco Mula2, Gail S Bell1, Josemir W Sander1,31Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom; 2Department of Clinical and Experimental Medicine, Division of Neurology, Amedeo Avogadro University, University Hospital Maggiore della Carità, Novara, Italy; 3SEIN – Epilepsy Institute in the Netherlands Foundation, Heemstede, The NetherlandsAbstract: Recently, the US Food and Drug Administration issued an alert about an increased risk for suicidality during treatment with antiepileptic drugs (AEDs) for different indications, including epilepsy. We discuss the issue of suicide in epilepsy with special attention to AEDs and the assessment of suicide in people with epilepsy. It has been suggested that early medical treatment with AEDs might potentially reduce suicide risk of people with epilepsy, but it is of great importance that the choice of drug is tailored to the mental state of the patient. The issue of suicidality in epilepsy is likely to represent an example of how the underdiagnosis of psychiatric symptoms, the lack of input from professionals (eg, psychologists, social workers, and psychiatrists), and the delay in an optimized AED therapy may worsen the prognosis of the condition with the occurrence of severe complications such as suicide.Keywords: epilepsy, suicide, adverse effect, depression Marco MulaGail S BellJosemir W SanderDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2010, Iss Issue 1, Pp 613-618 (2010)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Marco Mula
Gail S Bell
Josemir W Sander
Assessing suicidal risk with antiepileptic drugs
description Marco Mula2, Gail S Bell1, Josemir W Sander1,31Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom; 2Department of Clinical and Experimental Medicine, Division of Neurology, Amedeo Avogadro University, University Hospital Maggiore della Carità, Novara, Italy; 3SEIN – Epilepsy Institute in the Netherlands Foundation, Heemstede, The NetherlandsAbstract: Recently, the US Food and Drug Administration issued an alert about an increased risk for suicidality during treatment with antiepileptic drugs (AEDs) for different indications, including epilepsy. We discuss the issue of suicide in epilepsy with special attention to AEDs and the assessment of suicide in people with epilepsy. It has been suggested that early medical treatment with AEDs might potentially reduce suicide risk of people with epilepsy, but it is of great importance that the choice of drug is tailored to the mental state of the patient. The issue of suicidality in epilepsy is likely to represent an example of how the underdiagnosis of psychiatric symptoms, the lack of input from professionals (eg, psychologists, social workers, and psychiatrists), and the delay in an optimized AED therapy may worsen the prognosis of the condition with the occurrence of severe complications such as suicide.Keywords: epilepsy, suicide, adverse effect, depression
format article
author Marco Mula
Gail S Bell
Josemir W Sander
author_facet Marco Mula
Gail S Bell
Josemir W Sander
author_sort Marco Mula
title Assessing suicidal risk with antiepileptic drugs
title_short Assessing suicidal risk with antiepileptic drugs
title_full Assessing suicidal risk with antiepileptic drugs
title_fullStr Assessing suicidal risk with antiepileptic drugs
title_full_unstemmed Assessing suicidal risk with antiepileptic drugs
title_sort assessing suicidal risk with antiepileptic drugs
publisher Dove Medical Press
publishDate 2010
url https://doaj.org/article/98914a0b680d4ade83e1ffc2b73a0848
work_keys_str_mv AT marcomula assessingsuicidalriskwithantiepilepticdrugs
AT gailsbell assessingsuicidalriskwithantiepilepticdrugs
AT josemirwsander assessingsuicidalriskwithantiepilepticdrugs
_version_ 1718400485816270848