Assessing suicidal risk with antiepileptic drugs
Marco Mula2, Gail S Bell1, Josemir W Sander1,31Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom; 2Department of Clinical and Experimental Medicine, Division o...
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Dove Medical Press
2010
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oai:doaj.org-article:98914a0b680d4ade83e1ffc2b73a08482021-12-02T05:15:24ZAssessing suicidal risk with antiepileptic drugs1176-63281178-2021https://doaj.org/article/98914a0b680d4ade83e1ffc2b73a08482010-09-01T00:00:00Zhttp://www.dovepress.com/assessing-suicidal-risk-with-antiepileptic-drugs-a5270https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Marco Mula2, Gail S Bell1, Josemir W Sander1,31Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom; 2Department of Clinical and Experimental Medicine, Division of Neurology, Amedeo Avogadro University, University Hospital Maggiore della Carità, Novara, Italy; 3SEIN – Epilepsy Institute in the Netherlands Foundation, Heemstede, The NetherlandsAbstract: Recently, the US Food and Drug Administration issued an alert about an increased risk for suicidality during treatment with antiepileptic drugs (AEDs) for different indications, including epilepsy. We discuss the issue of suicide in epilepsy with special attention to AEDs and the assessment of suicide in people with epilepsy. It has been suggested that early medical treatment with AEDs might potentially reduce suicide risk of people with epilepsy, but it is of great importance that the choice of drug is tailored to the mental state of the patient. The issue of suicidality in epilepsy is likely to represent an example of how the underdiagnosis of psychiatric symptoms, the lack of input from professionals (eg, psychologists, social workers, and psychiatrists), and the delay in an optimized AED therapy may worsen the prognosis of the condition with the occurrence of severe complications such as suicide.Keywords: epilepsy, suicide, adverse effect, depression Marco MulaGail S BellJosemir W SanderDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2010, Iss Issue 1, Pp 613-618 (2010) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Marco Mula Gail S Bell Josemir W Sander Assessing suicidal risk with antiepileptic drugs |
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Marco Mula2, Gail S Bell1, Josemir W Sander1,31Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom; 2Department of Clinical and Experimental Medicine, Division of Neurology, Amedeo Avogadro University, University Hospital Maggiore della Carità, Novara, Italy; 3SEIN – Epilepsy Institute in the Netherlands Foundation, Heemstede, The NetherlandsAbstract: Recently, the US Food and Drug Administration issued an alert about an increased risk for suicidality during treatment with antiepileptic drugs (AEDs) for different indications, including epilepsy. We discuss the issue of suicide in epilepsy with special attention to AEDs and the assessment of suicide in people with epilepsy. It has been suggested that early medical treatment with AEDs might potentially reduce suicide risk of people with epilepsy, but it is of great importance that the choice of drug is tailored to the mental state of the patient. The issue of suicidality in epilepsy is likely to represent an example of how the underdiagnosis of psychiatric symptoms, the lack of input from professionals (eg, psychologists, social workers, and psychiatrists), and the delay in an optimized AED therapy may worsen the prognosis of the condition with the occurrence of severe complications such as suicide.Keywords: epilepsy, suicide, adverse effect, depression |
format |
article |
author |
Marco Mula Gail S Bell Josemir W Sander |
author_facet |
Marco Mula Gail S Bell Josemir W Sander |
author_sort |
Marco Mula |
title |
Assessing suicidal risk with antiepileptic drugs |
title_short |
Assessing suicidal risk with antiepileptic drugs |
title_full |
Assessing suicidal risk with antiepileptic drugs |
title_fullStr |
Assessing suicidal risk with antiepileptic drugs |
title_full_unstemmed |
Assessing suicidal risk with antiepileptic drugs |
title_sort |
assessing suicidal risk with antiepileptic drugs |
publisher |
Dove Medical Press |
publishDate |
2010 |
url |
https://doaj.org/article/98914a0b680d4ade83e1ffc2b73a0848 |
work_keys_str_mv |
AT marcomula assessingsuicidalriskwithantiepilepticdrugs AT gailsbell assessingsuicidalriskwithantiepilepticdrugs AT josemirwsander assessingsuicidalriskwithantiepilepticdrugs |
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1718400485816270848 |