Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease.

Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease.

<h4>Background</h4>Alzheimer's Disease (AD) is the most common neurodegenerative disease and the leading cause of dementia among senile subjects. It has been proposed that AD can be caused by defects in mitochondrial oxidative phosphorylation. Given the fundamental contribution of t...

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Main Authors: Aurelia Santoro, Valentina Balbi, Elisa Balducci, Chiara Pirazzini, Francesca Rosini, Francesca Tavano, Alessandro Achilli, Paola Siviero, Nadia Minicuci, Elena Bellavista, Michele Mishto, Stefano Salvioli, Francesca Marchegiani, Maurizio Cardelli, Fabiola Olivieri, Benedetta Nacmias, Andrea Maria Chiamenti, Luisa Benussi, Roberta Ghidoni, Giuseppina Rose, Carlo Gabelli, Giuliano Binetti, Sandro Sorbi, Gaetano Crepaldi, Giuseppe Passarino, Antonio Torroni, Claudio Franceschi
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/9894e1651792487a9699a941862fe2c6
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