Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma.

Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma.

Mesenchymal chondrosarcomas (MCs) account for 3-10% of primary chondrosarcomas. The cytogenetic literature includes only ten such tumours with karyotypic information and no specific aberrations have been identified. Using a purely molecular genetic approach a HEY1-NCOA2 fusion gene was recently dete...

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Auteurs principaux: Kaja B Nyquist, Ioannis Panagopoulos, Jim Thorsen, Lisbeth Haugom, Ludmila Gorunova, Bodil Bjerkehagen, Alexander Fosså, Marianne Guriby, Torfinn Nome, Ragnhild A Lothe, Rolf I Skotheim, Sverre Heim, Francesca Micci
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/98a9409dd9a44e368c00c0740b99fb50
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https://doaj.org/article/98a9409dd9a44e368c00c0740b99fb50

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