Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions
Abstract Novel platelet and megakaryocyte transcriptome analysis allows prediction of the full or theoretical proteome of a representative human platelet. Here, we integrated the established platelet proteomes from six cohorts of healthy subjects, encompassing 5.2 k proteins, with two novel genome-w...
Guardado en:
Autores principales: | Jingnan Huang, Frauke Swieringa, Fiorella A. Solari, Isabella Provenzale, Luigi Grassi, Ilaria De Simone, Constance C. F. M. J. Baaten, Rachel Cavill, Albert Sickmann, Mattia Frontini, Johan W. M. Heemskerk |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/98b564f1b944467ca88a30f85c123905 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The heterogeneity of megakaryocytes and platelets and implications for ex vivo platelet generation
por: Cuicui Liu, et al.
Publicado: (2021) -
Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome
por: Johanna P. van Geffen, et al.
Publicado: (2020) -
Platelet function is modified by common sequence variation in megakaryocyte super enhancers
por: Romina Petersen, et al.
Publicado: (2017) -
Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p
por: Mingyi Qu, et al.
Publicado: (2020) -
Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP
por: Moyra Lawrence, et al.
Publicado: (2021)