Interaction of Klebsiella pneumoniae with tissue macrophages in a mouse infection model and ex-vivo pig organ perfusions: an exploratory investigation

Summary: Background: Hypervirulent Klebsiella pneumoniae (hvKp) strains of capsule type K1 and K2 cause invasive infections associated with hepatic abscesses, which can be difficult to treat and are frequently associated with relapsing infections. Other K pneumoniae strains (non-hvKp), including li...

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Main Authors: Joseph J Wanford, PhD, Ryan G Hames, BSc, David Carreno, PhD, Zydrune Jasiunaite, BSc, Wen Y Chung, PhD, Fabio Arena, MD, Vincenzo Di Pilato, PhD, Kornelis Straatman, PhD, Kevin West, ProfPhD, Robeena Farzand, PhD, Mariagrazia Pizza, MA, Luisa Martinez-Pomares, PhD, Peter W Andrew, ProfPhD, E Richard Moxon, ProfFRS, Ashley R Dennison, ProfMD, Gian Maria Rossolini, ProfMD, Marco R Oggioni, ProfMD
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/98b688093a574746b4bdada9d71052cd
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