Polyandry blocks gene drive in a wild house mouse population
This study resolves a long-standing mystery of why t haplotypes, an example of selfish genes, have persisted at unexpectedly low frequencies in wild mouse populations. It shows that multiple mating by females, which is more common at higher mouse population densities, decreases the frequency of driv...
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Nature Portfolio
2020
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oai:doaj.org-article:98bb2f358d3e49a7ad84dfb82ec1281a2021-12-02T17:33:12ZPolyandry blocks gene drive in a wild house mouse population10.1038/s41467-020-18967-82041-1723https://doaj.org/article/98bb2f358d3e49a7ad84dfb82ec1281a2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18967-8https://doaj.org/toc/2041-1723This study resolves a long-standing mystery of why t haplotypes, an example of selfish genes, have persisted at unexpectedly low frequencies in wild mouse populations. It shows that multiple mating by females, which is more common at higher mouse population densities, decreases the frequency of driving t haplotypes.Andri ManserBarbara KönigAnna K. LindholmNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020) |
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Science Q Andri Manser Barbara König Anna K. Lindholm Polyandry blocks gene drive in a wild house mouse population |
description |
This study resolves a long-standing mystery of why t haplotypes, an example of selfish genes, have persisted at unexpectedly low frequencies in wild mouse populations. It shows that multiple mating by females, which is more common at higher mouse population densities, decreases the frequency of driving t haplotypes. |
format |
article |
author |
Andri Manser Barbara König Anna K. Lindholm |
author_facet |
Andri Manser Barbara König Anna K. Lindholm |
author_sort |
Andri Manser |
title |
Polyandry blocks gene drive in a wild house mouse population |
title_short |
Polyandry blocks gene drive in a wild house mouse population |
title_full |
Polyandry blocks gene drive in a wild house mouse population |
title_fullStr |
Polyandry blocks gene drive in a wild house mouse population |
title_full_unstemmed |
Polyandry blocks gene drive in a wild house mouse population |
title_sort |
polyandry blocks gene drive in a wild house mouse population |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/98bb2f358d3e49a7ad84dfb82ec1281a |
work_keys_str_mv |
AT andrimanser polyandryblocksgenedriveinawildhousemousepopulation AT barbarakonig polyandryblocksgenedriveinawildhousemousepopulation AT annaklindholm polyandryblocksgenedriveinawildhousemousepopulation |
_version_ |
1718380013911277568 |