Polyandry blocks gene drive in a wild house mouse population

This study resolves a long-standing mystery of why t haplotypes, an example of selfish genes, have persisted at unexpectedly low frequencies in wild mouse populations. It shows that multiple mating by females, which is more common at higher mouse population densities, decreases the frequency of driv...

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Auteurs principaux:	Andri Manser, Barbara König, Anna K. Lindholm
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/98bb2f358d3e49a7ad84dfb82ec1281a
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spelling	oai:doaj.org-article:98bb2f358d3e49a7ad84dfb82ec1281a2021-12-02T17:33:12ZPolyandry blocks gene drive in a wild house mouse population10.1038/s41467-020-18967-82041-1723https://doaj.org/article/98bb2f358d3e49a7ad84dfb82ec1281a2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18967-8https://doaj.org/toc/2041-1723This study resolves a long-standing mystery of why t haplotypes, an example of selfish genes, have persisted at unexpectedly low frequencies in wild mouse populations. It shows that multiple mating by females, which is more common at higher mouse population densities, decreases the frequency of driving t haplotypes.Andri ManserBarbara KönigAnna K. LindholmNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andri Manser Barbara König Anna K. Lindholm Polyandry blocks gene drive in a wild house mouse population
description	This study resolves a long-standing mystery of why t haplotypes, an example of selfish genes, have persisted at unexpectedly low frequencies in wild mouse populations. It shows that multiple mating by females, which is more common at higher mouse population densities, decreases the frequency of driving t haplotypes.
format	article
author	Andri Manser Barbara König Anna K. Lindholm
author_facet	Andri Manser Barbara König Anna K. Lindholm
author_sort	Andri Manser
title	Polyandry blocks gene drive in a wild house mouse population
title_short	Polyandry blocks gene drive in a wild house mouse population
title_full	Polyandry blocks gene drive in a wild house mouse population
title_fullStr	Polyandry blocks gene drive in a wild house mouse population
title_full_unstemmed	Polyandry blocks gene drive in a wild house mouse population
title_sort	polyandry blocks gene drive in a wild house mouse population
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/98bb2f358d3e49a7ad84dfb82ec1281a
work_keys_str_mv	AT andrimanser polyandryblocksgenedriveinawildhousemousepopulation AT barbarakonig polyandryblocksgenedriveinawildhousemousepopulation AT annaklindholm polyandryblocksgenedriveinawildhousemousepopulation
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Polyandry blocks gene drive in a wild house mouse population

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