Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.

Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.

Late-onset Alzheimer's disease (LOAD) is the most common type of dementia causing irreversible brain damage to the elderly and presents a major public health challenge. Clinical research and genome-wide association studies have suggested a potential contribution of the endocytic pathway to AD,...

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Detalles Bibliográficos
Autores principales: Lingyu Zhan, Jiajin Li, Brandon Jew, Jae Hoon Sul
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/98c878374d6c4512ba04482ca1e6ae92
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