Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia

Molecular mechanisms of macrophage-mediated regulation of artery growth in response to ischemia are poorly understood. Here the authors show that vascular endothelium controls macrophage maturation and differentiation via Notch signaling, which in turn promotes arteriogenesis and ischemic tissue rec...

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Autores principales:	Kashyap Krishnasamy, Anne Limbourg, Tamar Kapanadze, Jaba Gamrekelashvili, Christian Beger, Christine Häger, Vladimir J. Lozanovski, Christine S. Falk, L. Christian Napp, Johann Bauersachs, Matthias Mack, Hermann Haller, Christian Weber, Ralf H. Adams, Florian P. Limbourg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/98cda6910c484a9693175095f267419e
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spelling	oai:doaj.org-article:98cda6910c484a9693175095f267419e2021-12-02T14:42:05ZBlood vessel control of macrophage maturation promotes arteriogenesis in ischemia10.1038/s41467-017-00953-22041-1723https://doaj.org/article/98cda6910c484a9693175095f267419e2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00953-2https://doaj.org/toc/2041-1723Molecular mechanisms of macrophage-mediated regulation of artery growth in response to ischemia are poorly understood. Here the authors show that vascular endothelium controls macrophage maturation and differentiation via Notch signaling, which in turn promotes arteriogenesis and ischemic tissue recovery.Kashyap KrishnasamyAnne LimbourgTamar KapanadzeJaba GamrekelashviliChristian BegerChristine HägerVladimir J. LozanovskiChristine S. FalkL. Christian NappJohann BauersachsMatthias MackHermann HallerChristian WeberRalf H. AdamsFlorian P. LimbourgNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kashyap Krishnasamy Anne Limbourg Tamar Kapanadze Jaba Gamrekelashvili Christian Beger Christine Häger Vladimir J. Lozanovski Christine S. Falk L. Christian Napp Johann Bauersachs Matthias Mack Hermann Haller Christian Weber Ralf H. Adams Florian P. Limbourg Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
description	Molecular mechanisms of macrophage-mediated regulation of artery growth in response to ischemia are poorly understood. Here the authors show that vascular endothelium controls macrophage maturation and differentiation via Notch signaling, which in turn promotes arteriogenesis and ischemic tissue recovery.
format	article
author	Kashyap Krishnasamy Anne Limbourg Tamar Kapanadze Jaba Gamrekelashvili Christian Beger Christine Häger Vladimir J. Lozanovski Christine S. Falk L. Christian Napp Johann Bauersachs Matthias Mack Hermann Haller Christian Weber Ralf H. Adams Florian P. Limbourg
author_facet	Kashyap Krishnasamy Anne Limbourg Tamar Kapanadze Jaba Gamrekelashvili Christian Beger Christine Häger Vladimir J. Lozanovski Christine S. Falk L. Christian Napp Johann Bauersachs Matthias Mack Hermann Haller Christian Weber Ralf H. Adams Florian P. Limbourg
author_sort	Kashyap Krishnasamy
title	Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
title_short	Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
title_full	Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
title_fullStr	Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
title_full_unstemmed	Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
title_sort	blood vessel control of macrophage maturation promotes arteriogenesis in ischemia
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/98cda6910c484a9693175095f267419e
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Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia

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