ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES

The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resi...

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Autores principales: V. .. Sviridov, Ya. G. Razuvaeva, L. N. Shantanova
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2014
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Acceso en línea:https://doaj.org/article/98d4001f9d0b41408af1c79d1999a73c
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spelling oai:doaj.org-article:98d4001f9d0b41408af1c79d1999a73c2021-11-23T06:14:31ZANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES2541-94202587-9596https://doaj.org/article/98d4001f9d0b41408af1c79d1999a73c2014-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1841https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resistance of the experimental animals to hypoxias of different genesis. S. centauroides in the dose of 150 mg/kg has the most pronounced antihypoxic activity, increasing the lifespan of the animals with hemic and normobaric hypoxia on average by 60 % (p < 0,001) and and with histotoxic hypoxia - by 50 % (p < 0,001).V. .. SviridovYa. G. RazuvaevaL. N. ShantanovaScientific Сentre for Family Health and Human Reproduction Problemsarticleserratula centauroidesserratula centauroideshypoxic statesantihypoxic actionScienceQRUActa Biomedica Scientifica, Vol 0, Iss 6, Pp 77-79 (2014)
institution DOAJ
collection DOAJ
language RU
topic serratula centauroides
serratula centauroides
hypoxic states
antihypoxic action
Science
Q
spellingShingle serratula centauroides
serratula centauroides
hypoxic states
antihypoxic action
Science
Q
V. .. Sviridov
Ya. G. Razuvaeva
L. N. Shantanova
ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
description The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resistance of the experimental animals to hypoxias of different genesis. S. centauroides in the dose of 150 mg/kg has the most pronounced antihypoxic activity, increasing the lifespan of the animals with hemic and normobaric hypoxia on average by 60 % (p < 0,001) and and with histotoxic hypoxia - by 50 % (p < 0,001).
format article
author V. .. Sviridov
Ya. G. Razuvaeva
L. N. Shantanova
author_facet V. .. Sviridov
Ya. G. Razuvaeva
L. N. Shantanova
author_sort V. .. Sviridov
title ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_short ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_full ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_fullStr ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_full_unstemmed ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
title_sort antihypoxic properties of the dry extract from serratula centauroides
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2014
url https://doaj.org/article/98d4001f9d0b41408af1c79d1999a73c
work_keys_str_mv AT vsviridov antihypoxicpropertiesofthedryextractfromserratulacentauroides
AT yagrazuvaeva antihypoxicpropertiesofthedryextractfromserratulacentauroides
AT lnshantanova antihypoxicpropertiesofthedryextractfromserratulacentauroides
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