Simultaneous Coinfection of Macaques with Zika and Dengue Viruses Does not Enhance Acute Plasma Viremia but Leads to Activation of Monocyte Subsets and Biphasic Release of Pro-inflammatory Cytokines
Abstract The consequences of simultaneous infection with Zika (ZIKV) and Dengue (DENV) viruses are poorly understood. Here we show that rhesus macaques experimentally coinfected simultaneously with ZIKV and DENV-2 demonstrated ZIKV or DENV replication without an enhancement of either infection. Coin...
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Auteurs principaux: | William G. Valiant, Mary J. Mattapallil, Stephen Higgs, Yan-Jang S. Huang, Dana L. Vanlandingham, Mark G. Lewis, Joseph J. Mattapallil |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/98da3e2a93a84a69b1d1d0c93ea35080 |
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