Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy

Introduction: Percutaneous nephrolithotomy (PNL) is widely used for kidney stones. One of the complications of PNL is Systemic inflammatory response syndrome (SIRS), which is of great importance. Here we wanted to estimate the effectiveness of neutrophil to lymphocyte ratio (NLR) and platelet-to-lym...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mehrdad Mohammadi Sichani, Mohammad Ali Vakili, Mohammad Hatef Khorrami, Mohammad-Hossein Izadpanahi, Farshad Gholipour, Reza Kazemi
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2021
Materias:	systemic inflammatory response syndrome percutaneous nephrolithotomy neutrophil to lymphocyte ratio platelet to lymphocyte ratio Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/98e5d9a8b5b6471ca3134a7b799ac96a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:98e5d9a8b5b6471ca3134a7b799ac96a
record_format	dspace
spelling	oai:doaj.org-article:98e5d9a8b5b6471ca3134a7b799ac96a2021-11-30T08:56:42ZPredictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy10.22034/TRU.2021.306802.10832717-042Xhttps://doaj.org/article/98e5d9a8b5b6471ca3134a7b799ac96a2021-11-01T00:00:00Zhttps://www.transresurology.com/article_138461.htmlhttps://doaj.org/toc/2717-042XIntroduction: Percutaneous nephrolithotomy (PNL) is widely used for kidney stones. One of the complications of PNL is Systemic inflammatory response syndrome (SIRS), which is of great importance. Here we wanted to estimate the effectiveness of neutrophil to lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting SIRS following PNL. Methods: This study is prospective observational work done in 2018-2019 in Isfahan, Iran, on patients diagnosed with kidney stones that were candidates of PNL. We collected patient demographic data, including gender, age, and size of kidney stones. Information about the operation duration, procedures, and laboratory data were collected before and after the procedures. All data were compared between patients with or without SIRS after PNL. Results: In the present study, 152 candidates for PNL entered the research. The average age of the patients was 52.1± 13.4 years. In this study, 95 patients (62.5%) were male, and 57 (37.5%) were female. The average stone size was 29.4± 5.3 mm. Based on our data; 26 patients (17.1%) had sepsis after the procedure. There was only a significant difference between groups of patients regarding primary stone composition in the way that 92.3% of cases with sepsis had two stone compositions while 44.4% of other patients had two stone compositions and 50% had one stone composition (P-value<0.001). We found that patients that had sepsis after PNL had significantly higher operation duration (P-value=0.044) and significantly higher packed cell transfusion (30.8%) compared to other patients (4%) (P-value<0.001). The NLR below 72.2 could predict sepsis after PNL with 80.5% sensitivity and 33.3% specificity. Furthermore, the PLR below 63.3 could predict sepsis after PNL with 90.9% sensitivity and 5.3% specificity. Conclusion: Elevated NLR and PLR are associated with increased frequencies of SIRS after PNL. These data could be used effectively in predicting SIRS in these patients.Mehrdad Mohammadi Sichani Mohammad Ali VakiliMohammad Hatef KhorramiMohammad-Hossein IzadpanahiFarshad GholipourReza Kazemi Urology Research Centerarticlesystemic inflammatory response syndromepercutaneous nephrolithotomyneutrophil to lymphocyte ratioplatelet to lymphocyte ratioDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 3, Iss 4, Pp 154-160 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	systemic inflammatory response syndrome percutaneous nephrolithotomy neutrophil to lymphocyte ratio platelet to lymphocyte ratio Diseases of the genitourinary system. Urology RC870-923
spellingShingle	systemic inflammatory response syndrome percutaneous nephrolithotomy neutrophil to lymphocyte ratio platelet to lymphocyte ratio Diseases of the genitourinary system. Urology RC870-923 Mehrdad Mohammadi Sichani Mohammad Ali Vakili Mohammad Hatef Khorrami Mohammad-Hossein Izadpanahi Farshad Gholipour Reza Kazemi Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy
description	Introduction: Percutaneous nephrolithotomy (PNL) is widely used for kidney stones. One of the complications of PNL is Systemic inflammatory response syndrome (SIRS), which is of great importance. Here we wanted to estimate the effectiveness of neutrophil to lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting SIRS following PNL. Methods: This study is prospective observational work done in 2018-2019 in Isfahan, Iran, on patients diagnosed with kidney stones that were candidates of PNL. We collected patient demographic data, including gender, age, and size of kidney stones. Information about the operation duration, procedures, and laboratory data were collected before and after the procedures. All data were compared between patients with or without SIRS after PNL. Results: In the present study, 152 candidates for PNL entered the research. The average age of the patients was 52.1± 13.4 years. In this study, 95 patients (62.5%) were male, and 57 (37.5%) were female. The average stone size was 29.4± 5.3 mm. Based on our data; 26 patients (17.1%) had sepsis after the procedure. There was only a significant difference between groups of patients regarding primary stone composition in the way that 92.3% of cases with sepsis had two stone compositions while 44.4% of other patients had two stone compositions and 50% had one stone composition (P-value<0.001). We found that patients that had sepsis after PNL had significantly higher operation duration (P-value=0.044) and significantly higher packed cell transfusion (30.8%) compared to other patients (4%) (P-value<0.001). The NLR below 72.2 could predict sepsis after PNL with 80.5% sensitivity and 33.3% specificity. Furthermore, the PLR below 63.3 could predict sepsis after PNL with 90.9% sensitivity and 5.3% specificity. Conclusion: Elevated NLR and PLR are associated with increased frequencies of SIRS after PNL. These data could be used effectively in predicting SIRS in these patients.
format	article
author	Mehrdad Mohammadi Sichani Mohammad Ali Vakili Mohammad Hatef Khorrami Mohammad-Hossein Izadpanahi Farshad Gholipour Reza Kazemi
author_facet	Mehrdad Mohammadi Sichani Mohammad Ali Vakili Mohammad Hatef Khorrami Mohammad-Hossein Izadpanahi Farshad Gholipour Reza Kazemi
author_sort	Mehrdad Mohammadi Sichani
title	Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy
title_short	Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy
title_full	Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy
title_fullStr	Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy
title_full_unstemmed	Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy
title_sort	predictive values of neutrophil to lymphocyte ratio and platelet-to-lymphocyte ratio for systemic inflammatory response syndrome after percutaneous nephrolithotomy
publisher	Urology Research Center
publishDate	2021
url	https://doaj.org/article/98e5d9a8b5b6471ca3134a7b799ac96a
work_keys_str_mv	AT mehrdadmohammadisichani predictivevaluesofneutrophiltolymphocyteratioandplatelettolymphocyteratioforsystemicinflammatoryresponsesyndromeafterpercutaneousnephrolithotomy AT mohammadalivakili predictivevaluesofneutrophiltolymphocyteratioandplatelettolymphocyteratioforsystemicinflammatoryresponsesyndromeafterpercutaneousnephrolithotomy AT mohammadhatefkhorrami predictivevaluesofneutrophiltolymphocyteratioandplatelettolymphocyteratioforsystemicinflammatoryresponsesyndromeafterpercutaneousnephrolithotomy AT mohammadhosseinizadpanahi predictivevaluesofneutrophiltolymphocyteratioandplatelettolymphocyteratioforsystemicinflammatoryresponsesyndromeafterpercutaneousnephrolithotomy AT farshadgholipour predictivevaluesofneutrophiltolymphocyteratioandplatelettolymphocyteratioforsystemicinflammatoryresponsesyndromeafterpercutaneousnephrolithotomy AT rezakazemi predictivevaluesofneutrophiltolymphocyteratioandplatelettolymphocyteratioforsystemicinflammatoryresponsesyndromeafterpercutaneousnephrolithotomy
_version_	1718406699348393984

Predictive Values of Neutrophil to Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy

Ejemplares similares