The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules

In Drosophila, Fasciclin 2 (Fas2) has been mainly studied in the nervous system, yet this adhesion protein is more abundant in the adult renal tubule. Here the authors show that Fas2 is essential for brush border maintenance in renal tubules through regulation of microvilli length and organization.

Guardado en:

Detalles Bibliográficos
Autores principales:	Kenneth A. Halberg, Stephanie M. Rainey, Iben R. Veland, Helen Neuert, Anthony J. Dornan, Christian Klämbt, Shireen-Anne Davies, Julian A. T. Dow
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/98ef0f6e7891438ba23e4976f6bc4b84
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:98ef0f6e7891438ba23e4976f6bc4b84
record_format	dspace
spelling	oai:doaj.org-article:98ef0f6e7891438ba23e4976f6bc4b842021-12-02T16:58:00ZThe cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules10.1038/ncomms112662041-1723https://doaj.org/article/98ef0f6e7891438ba23e4976f6bc4b842016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11266https://doaj.org/toc/2041-1723In Drosophila, Fasciclin 2 (Fas2) has been mainly studied in the nervous system, yet this adhesion protein is more abundant in the adult renal tubule. Here the authors show that Fas2 is essential for brush border maintenance in renal tubules through regulation of microvilli length and organization.Kenneth A. HalbergStephanie M. RaineyIben R. VelandHelen NeuertAnthony J. DornanChristian KlämbtShireen-Anne DaviesJulian A. T. DowNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kenneth A. Halberg Stephanie M. Rainey Iben R. Veland Helen Neuert Anthony J. Dornan Christian Klämbt Shireen-Anne Davies Julian A. T. Dow The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules
description	In Drosophila, Fasciclin 2 (Fas2) has been mainly studied in the nervous system, yet this adhesion protein is more abundant in the adult renal tubule. Here the authors show that Fas2 is essential for brush border maintenance in renal tubules through regulation of microvilli length and organization.
format	article
author	Kenneth A. Halberg Stephanie M. Rainey Iben R. Veland Helen Neuert Anthony J. Dornan Christian Klämbt Shireen-Anne Davies Julian A. T. Dow
author_facet	Kenneth A. Halberg Stephanie M. Rainey Iben R. Veland Helen Neuert Anthony J. Dornan Christian Klämbt Shireen-Anne Davies Julian A. T. Dow
author_sort	Kenneth A. Halberg
title	The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules
title_short	The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules
title_full	The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules
title_fullStr	The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules
title_full_unstemmed	The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules
title_sort	cell adhesion molecule fasciclin2 regulates brush border length and organization in drosophila renal tubules
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/98ef0f6e7891438ba23e4976f6bc4b84
work_keys_str_mv	AT kennethahalberg thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT stephaniemrainey thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT ibenrveland thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT helenneuert thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT anthonyjdornan thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT christianklambt thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT shireenannedavies thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT julianatdow thecelladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT kennethahalberg celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT stephaniemrainey celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT ibenrveland celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT helenneuert celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT anthonyjdornan celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT christianklambt celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT shireenannedavies celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules AT julianatdow celladhesionmoleculefasciclin2regulatesbrushborderlengthandorganizationindrosophilarenaltubules
_version_	1718382403502735360

The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules

Ejemplares similares