Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα)

Background: As a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, lithospermic acid (LA) has been identified as the pharmacological management for neuroprotection and hepatoprotection. However, the role and mechanism of lithospermic acid in the pathological proces...

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Main Authors: Min Zhang, Li Wei, Saiyang Xie, Yun Xing, Wenke Shi, Xiaofeng Zeng, Si Chen, Shasha Wang, Wei Deng, Qizhu Tang
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/98fe9b35e9cd43eb9ebf58f6fd0ba930
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