Automated cell count in body fluids: a review

Body fluid cell counting provides valuable information for the diagnosis and treatment of a variety of conditions. Chamber cell count and cellularity analysis by optical microscopy are considered the gold-standard method for cell counting. However, this method has a long turnaround time and limited...

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Autores principales:	Alcaide Martín María José, Altimira Queral Laura, Sahuquillo Frías Laura, Valiña Amado Laura, Merino Anna, García de Guadiana-Romualdo Luis
Formato:	article
Lenguaje:	EN ES
Publicado:	De Gruyter 2021
Materias:	automated cell count body fluids chamber count optical microscopy Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/9901702270df4d7d9b613fff79a50a53
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spelling	oai:doaj.org-article:9901702270df4d7d9b613fff79a50a532021-12-05T14:10:39ZAutomated cell count in body fluids: a review2628-491X10.1515/almed-2021-0011https://doaj.org/article/9901702270df4d7d9b613fff79a50a532021-03-01T00:00:00Zhttps://doi.org/10.1515/almed-2021-0011https://doaj.org/toc/2628-491XBody fluid cell counting provides valuable information for the diagnosis and treatment of a variety of conditions. Chamber cell count and cellularity analysis by optical microscopy are considered the gold-standard method for cell counting. However, this method has a long turnaround time and limited reproducibility, and requires highly-trained personnel. In the recent decades, specific modes have been developed for the analysis of body fluids. These modes, which perform automated cell counting, are incorporated into hemocytometers and urine analyzers. These innovations have been rapidly incorporated into routine laboratory practice. At present, a variety of analyzers are available that enable automated cell counting for body fluids. Nevertheless, these analyzers have some limitations and can only be operated by highly-qualified laboratory professionals. In this review, we provide an overview of the most relevant automated cell counters currently available for body fluids, the interpretation of the parameters measured by these analyzers, their main analytical features, and the role of optical microscopy as automated cell counters gain ground.Alcaide Martín María JoséAltimira Queral LauraSahuquillo Frías LauraValiña Amado LauraMerino AnnaGarcía de Guadiana-Romualdo LuisDe Gruyterarticleautomated cell countbody fluidschamber countoptical microscopyMedical technologyR855-855.5ENESAdvances in Laboratory Medicine, Vol 2, Iss 2, Pp 149-161 (2021)
institution	DOAJ
collection	DOAJ
language	EN ES
topic	automated cell count body fluids chamber count optical microscopy Medical technology R855-855.5
spellingShingle	automated cell count body fluids chamber count optical microscopy Medical technology R855-855.5 Alcaide Martín María José Altimira Queral Laura Sahuquillo Frías Laura Valiña Amado Laura Merino Anna García de Guadiana-Romualdo Luis Automated cell count in body fluids: a review
description	Body fluid cell counting provides valuable information for the diagnosis and treatment of a variety of conditions. Chamber cell count and cellularity analysis by optical microscopy are considered the gold-standard method for cell counting. However, this method has a long turnaround time and limited reproducibility, and requires highly-trained personnel. In the recent decades, specific modes have been developed for the analysis of body fluids. These modes, which perform automated cell counting, are incorporated into hemocytometers and urine analyzers. These innovations have been rapidly incorporated into routine laboratory practice. At present, a variety of analyzers are available that enable automated cell counting for body fluids. Nevertheless, these analyzers have some limitations and can only be operated by highly-qualified laboratory professionals. In this review, we provide an overview of the most relevant automated cell counters currently available for body fluids, the interpretation of the parameters measured by these analyzers, their main analytical features, and the role of optical microscopy as automated cell counters gain ground.
format	article
author	Alcaide Martín María José Altimira Queral Laura Sahuquillo Frías Laura Valiña Amado Laura Merino Anna García de Guadiana-Romualdo Luis
author_facet	Alcaide Martín María José Altimira Queral Laura Sahuquillo Frías Laura Valiña Amado Laura Merino Anna García de Guadiana-Romualdo Luis
author_sort	Alcaide Martín María José
title	Automated cell count in body fluids: a review
title_short	Automated cell count in body fluids: a review
title_full	Automated cell count in body fluids: a review
title_fullStr	Automated cell count in body fluids: a review
title_full_unstemmed	Automated cell count in body fluids: a review
title_sort	automated cell count in body fluids: a review
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/9901702270df4d7d9b613fff79a50a53
work_keys_str_mv	AT alcaidemartinmariajose automatedcellcountinbodyfluidsareview AT altimiraquerallaura automatedcellcountinbodyfluidsareview AT sahuquillofriaslaura automatedcellcountinbodyfluidsareview AT valinaamadolaura automatedcellcountinbodyfluidsareview AT merinoanna automatedcellcountinbodyfluidsareview AT garciadeguadianaromualdoluis automatedcellcountinbodyfluidsareview
_version_	1718371853216514048

Automated cell count in body fluids: a review

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