Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similarity of naive hiPSCs to their in vivo counterparts.
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2018
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oai:doaj.org-article:99050a32ab984d7caf964c0d037307432021-12-02T16:56:58ZParallel derivation of isogenic human primed and naive induced pluripotent stem cells10.1038/s41467-017-02107-w2041-1723https://doaj.org/article/99050a32ab984d7caf964c0d037307432018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02107-whttps://doaj.org/toc/2041-1723Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similarity of naive hiPSCs to their in vivo counterparts.Stéphanie KilensDimitri MeistermannDiego MorenoCaroline ChariauAnne GaignerieArnaud ReignierYohann LelièvreMiguel CasanovaCéline VallotSteven NedellecLéa FlippeJulie FirminJuan SongEric CharpentierJenna LammersAudrey DonnartNadège MarecWallid DebAudrey BihouéeCédric Le CaignecClaire PecqueurRichard RedonPaul BarrièreJérémie BourdonVincent PasqueMagali SoumillonTarjei S. MikkelsenClaire RougeulleThomas FréourLaurent DavidThe Milieu Intérieur ConsortiumNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
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Science Q Stéphanie Kilens Dimitri Meistermann Diego Moreno Caroline Chariau Anne Gaignerie Arnaud Reignier Yohann Lelièvre Miguel Casanova Céline Vallot Steven Nedellec Léa Flippe Julie Firmin Juan Song Eric Charpentier Jenna Lammers Audrey Donnart Nadège Marec Wallid Deb Audrey Bihouée Cédric Le Caignec Claire Pecqueur Richard Redon Paul Barrière Jérémie Bourdon Vincent Pasque Magali Soumillon Tarjei S. Mikkelsen Claire Rougeulle Thomas Fréour Laurent David The Milieu Intérieur Consortium Parallel derivation of isogenic human primed and naive induced pluripotent stem cells |
description |
Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similarity of naive hiPSCs to their in vivo counterparts. |
format |
article |
author |
Stéphanie Kilens Dimitri Meistermann Diego Moreno Caroline Chariau Anne Gaignerie Arnaud Reignier Yohann Lelièvre Miguel Casanova Céline Vallot Steven Nedellec Léa Flippe Julie Firmin Juan Song Eric Charpentier Jenna Lammers Audrey Donnart Nadège Marec Wallid Deb Audrey Bihouée Cédric Le Caignec Claire Pecqueur Richard Redon Paul Barrière Jérémie Bourdon Vincent Pasque Magali Soumillon Tarjei S. Mikkelsen Claire Rougeulle Thomas Fréour Laurent David The Milieu Intérieur Consortium |
author_facet |
Stéphanie Kilens Dimitri Meistermann Diego Moreno Caroline Chariau Anne Gaignerie Arnaud Reignier Yohann Lelièvre Miguel Casanova Céline Vallot Steven Nedellec Léa Flippe Julie Firmin Juan Song Eric Charpentier Jenna Lammers Audrey Donnart Nadège Marec Wallid Deb Audrey Bihouée Cédric Le Caignec Claire Pecqueur Richard Redon Paul Barrière Jérémie Bourdon Vincent Pasque Magali Soumillon Tarjei S. Mikkelsen Claire Rougeulle Thomas Fréour Laurent David The Milieu Intérieur Consortium |
author_sort |
Stéphanie Kilens |
title |
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells |
title_short |
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells |
title_full |
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells |
title_fullStr |
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells |
title_full_unstemmed |
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells |
title_sort |
parallel derivation of isogenic human primed and naive induced pluripotent stem cells |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/99050a32ab984d7caf964c0d03730743 |
work_keys_str_mv |
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