Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similarity of naive hiPSCs to their in vivo counterparts.

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Autores principales: Stéphanie Kilens, Dimitri Meistermann, Diego Moreno, Caroline Chariau, Anne Gaignerie, Arnaud Reignier, Yohann Lelièvre, Miguel Casanova, Céline Vallot, Steven Nedellec, Léa Flippe, Julie Firmin, Juan Song, Eric Charpentier, Jenna Lammers, Audrey Donnart, Nadège Marec, Wallid Deb, Audrey Bihouée, Cédric Le Caignec, Claire Pecqueur, Richard Redon, Paul Barrière, Jérémie Bourdon, Vincent Pasque, Magali Soumillon, Tarjei S. Mikkelsen, Claire Rougeulle, Thomas Fréour, Laurent David, The Milieu Intérieur Consortium
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Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/99050a32ab984d7caf964c0d03730743
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spelling oai:doaj.org-article:99050a32ab984d7caf964c0d037307432021-12-02T16:56:58ZParallel derivation of isogenic human primed and naive induced pluripotent stem cells10.1038/s41467-017-02107-w2041-1723https://doaj.org/article/99050a32ab984d7caf964c0d037307432018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02107-whttps://doaj.org/toc/2041-1723Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similarity of naive hiPSCs to their in vivo counterparts.Stéphanie KilensDimitri MeistermannDiego MorenoCaroline ChariauAnne GaignerieArnaud ReignierYohann LelièvreMiguel CasanovaCéline VallotSteven NedellecLéa FlippeJulie FirminJuan SongEric CharpentierJenna LammersAudrey DonnartNadège MarecWallid DebAudrey BihouéeCédric Le CaignecClaire PecqueurRichard RedonPaul BarrièreJérémie BourdonVincent PasqueMagali SoumillonTarjei S. MikkelsenClaire RougeulleThomas FréourLaurent DavidThe Milieu Intérieur ConsortiumNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stéphanie Kilens
Dimitri Meistermann
Diego Moreno
Caroline Chariau
Anne Gaignerie
Arnaud Reignier
Yohann Lelièvre
Miguel Casanova
Céline Vallot
Steven Nedellec
Léa Flippe
Julie Firmin
Juan Song
Eric Charpentier
Jenna Lammers
Audrey Donnart
Nadège Marec
Wallid Deb
Audrey Bihouée
Cédric Le Caignec
Claire Pecqueur
Richard Redon
Paul Barrière
Jérémie Bourdon
Vincent Pasque
Magali Soumillon
Tarjei S. Mikkelsen
Claire Rougeulle
Thomas Fréour
Laurent David
The Milieu Intérieur Consortium
Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
description Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similarity of naive hiPSCs to their in vivo counterparts.
format article
author Stéphanie Kilens
Dimitri Meistermann
Diego Moreno
Caroline Chariau
Anne Gaignerie
Arnaud Reignier
Yohann Lelièvre
Miguel Casanova
Céline Vallot
Steven Nedellec
Léa Flippe
Julie Firmin
Juan Song
Eric Charpentier
Jenna Lammers
Audrey Donnart
Nadège Marec
Wallid Deb
Audrey Bihouée
Cédric Le Caignec
Claire Pecqueur
Richard Redon
Paul Barrière
Jérémie Bourdon
Vincent Pasque
Magali Soumillon
Tarjei S. Mikkelsen
Claire Rougeulle
Thomas Fréour
Laurent David
The Milieu Intérieur Consortium
author_facet Stéphanie Kilens
Dimitri Meistermann
Diego Moreno
Caroline Chariau
Anne Gaignerie
Arnaud Reignier
Yohann Lelièvre
Miguel Casanova
Céline Vallot
Steven Nedellec
Léa Flippe
Julie Firmin
Juan Song
Eric Charpentier
Jenna Lammers
Audrey Donnart
Nadège Marec
Wallid Deb
Audrey Bihouée
Cédric Le Caignec
Claire Pecqueur
Richard Redon
Paul Barrière
Jérémie Bourdon
Vincent Pasque
Magali Soumillon
Tarjei S. Mikkelsen
Claire Rougeulle
Thomas Fréour
Laurent David
The Milieu Intérieur Consortium
author_sort Stéphanie Kilens
title Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
title_short Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
title_full Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
title_fullStr Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
title_full_unstemmed Parallel derivation of isogenic human primed and naive induced pluripotent stem cells
title_sort parallel derivation of isogenic human primed and naive induced pluripotent stem cells
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/99050a32ab984d7caf964c0d03730743
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