Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response

Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response

Oropouche virus (OROV) is an emerging arbovirus in South and Central Americas with high spreading potential. OROV infection has been associated with neurological complications and OROV genomic RNA has been detected in cerebrospinal fluid from patients, suggesting its neuroinvasive potential. Motivat...

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Main Authors: Glaucia M. Almeida, Juliano P. Souza, Niele D. Mendes, Marjorie C. Pontelli, Nathalia R. Pinheiro, Giovanna O. Nogueira, Ricardo S. Cardoso, Isadora M. Paiva, Gustavo D. Ferrari, Flávio P. Veras, Fernando Q. Cunha, Jose A. C. Horta-Junior, Luciane C. Alberici, Thiago M. Cunha, Guilherme G. Podolsky-Gondim, Luciano Neder, Eurico Arruda, Adriano Sebollela
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
arboviruses
viral encephalitis
histocultures
neuroinflammation
neuroinfection
neurotropic virus
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Online Access:https://doaj.org/article/9906ed265b86407d84abf4ac068b9fc7
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https://doaj.org/article/9906ed265b86407d84abf4ac068b9fc7

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