Cloaking nanoparticles with protein corona shield for targeted drug delivery

The efficacy of nanoparticles can be significantly inhibited by serum proteins binding to them. Here, the author developed a supramolecularly constructed protein corona on nanoparticles, which minimises interactions with serum proteins to prevent the clearance of these particles by macrophages.

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Autores principales:	Jun Yong Oh, Han Sol Kim, L. Palanikumar, Eun Min Go, Batakrishna Jana, Soo Ah Park, Ho Young Kim, Kibeom Kim, Jeong Kon Seo, Sang Kyu Kwak, Chaekyu Kim, Sebyung Kang, Ja-Hyoung Ryu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/990779936dde4d118e6b9a14546a8eef
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spelling	oai:doaj.org-article:990779936dde4d118e6b9a14546a8eef2021-12-02T15:33:54ZCloaking nanoparticles with protein corona shield for targeted drug delivery10.1038/s41467-018-06979-42041-1723https://doaj.org/article/990779936dde4d118e6b9a14546a8eef2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06979-4https://doaj.org/toc/2041-1723The efficacy of nanoparticles can be significantly inhibited by serum proteins binding to them. Here, the author developed a supramolecularly constructed protein corona on nanoparticles, which minimises interactions with serum proteins to prevent the clearance of these particles by macrophages.Jun Yong OhHan Sol KimL. PalanikumarEun Min GoBatakrishna JanaSoo Ah ParkHo Young KimKibeom KimJeong Kon SeoSang Kyu KwakChaekyu KimSebyung KangJa-Hyoung RyuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jun Yong Oh Han Sol Kim L. Palanikumar Eun Min Go Batakrishna Jana Soo Ah Park Ho Young Kim Kibeom Kim Jeong Kon Seo Sang Kyu Kwak Chaekyu Kim Sebyung Kang Ja-Hyoung Ryu Cloaking nanoparticles with protein corona shield for targeted drug delivery
description	The efficacy of nanoparticles can be significantly inhibited by serum proteins binding to them. Here, the author developed a supramolecularly constructed protein corona on nanoparticles, which minimises interactions with serum proteins to prevent the clearance of these particles by macrophages.
format	article
author	Jun Yong Oh Han Sol Kim L. Palanikumar Eun Min Go Batakrishna Jana Soo Ah Park Ho Young Kim Kibeom Kim Jeong Kon Seo Sang Kyu Kwak Chaekyu Kim Sebyung Kang Ja-Hyoung Ryu
author_facet	Jun Yong Oh Han Sol Kim L. Palanikumar Eun Min Go Batakrishna Jana Soo Ah Park Ho Young Kim Kibeom Kim Jeong Kon Seo Sang Kyu Kwak Chaekyu Kim Sebyung Kang Ja-Hyoung Ryu
author_sort	Jun Yong Oh
title	Cloaking nanoparticles with protein corona shield for targeted drug delivery
title_short	Cloaking nanoparticles with protein corona shield for targeted drug delivery
title_full	Cloaking nanoparticles with protein corona shield for targeted drug delivery
title_fullStr	Cloaking nanoparticles with protein corona shield for targeted drug delivery
title_full_unstemmed	Cloaking nanoparticles with protein corona shield for targeted drug delivery
title_sort	cloaking nanoparticles with protein corona shield for targeted drug delivery
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/990779936dde4d118e6b9a14546a8eef
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Cloaking nanoparticles with protein corona shield for targeted drug delivery

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