Lineage dynamics of murine pancreatic development at single-cell resolution

Coordinated proliferation and differentiation of diverse cell populations drive pancreatic epithelial and mesenchymal development. Here, the authors profile cell type dynamics in the developing mouse pancreas using single-cell RNA sequencing, identifying mesenchymal subtypes and undescribed endocrin...

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Autores principales: Lauren E. Byrnes, Daniel M. Wong, Meena Subramaniam, Nathaniel P. Meyer, Caroline L. Gilchrist, Sarah M. Knox, Aaron D. Tward, Chun J. Ye, Julie B. Sneddon
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9908253a395045fca4eafe9adba9fcf4
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spelling oai:doaj.org-article:9908253a395045fca4eafe9adba9fcf42021-12-02T16:56:43ZLineage dynamics of murine pancreatic development at single-cell resolution10.1038/s41467-018-06176-32041-1723https://doaj.org/article/9908253a395045fca4eafe9adba9fcf42018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06176-3https://doaj.org/toc/2041-1723Coordinated proliferation and differentiation of diverse cell populations drive pancreatic epithelial and mesenchymal development. Here, the authors profile cell type dynamics in the developing mouse pancreas using single-cell RNA sequencing, identifying mesenchymal subtypes and undescribed endocrine progenitors.Lauren E. ByrnesDaniel M. WongMeena SubramaniamNathaniel P. MeyerCaroline L. GilchristSarah M. KnoxAaron D. TwardChun J. YeJulie B. SneddonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lauren E. Byrnes
Daniel M. Wong
Meena Subramaniam
Nathaniel P. Meyer
Caroline L. Gilchrist
Sarah M. Knox
Aaron D. Tward
Chun J. Ye
Julie B. Sneddon
Lineage dynamics of murine pancreatic development at single-cell resolution
description Coordinated proliferation and differentiation of diverse cell populations drive pancreatic epithelial and mesenchymal development. Here, the authors profile cell type dynamics in the developing mouse pancreas using single-cell RNA sequencing, identifying mesenchymal subtypes and undescribed endocrine progenitors.
format article
author Lauren E. Byrnes
Daniel M. Wong
Meena Subramaniam
Nathaniel P. Meyer
Caroline L. Gilchrist
Sarah M. Knox
Aaron D. Tward
Chun J. Ye
Julie B. Sneddon
author_facet Lauren E. Byrnes
Daniel M. Wong
Meena Subramaniam
Nathaniel P. Meyer
Caroline L. Gilchrist
Sarah M. Knox
Aaron D. Tward
Chun J. Ye
Julie B. Sneddon
author_sort Lauren E. Byrnes
title Lineage dynamics of murine pancreatic development at single-cell resolution
title_short Lineage dynamics of murine pancreatic development at single-cell resolution
title_full Lineage dynamics of murine pancreatic development at single-cell resolution
title_fullStr Lineage dynamics of murine pancreatic development at single-cell resolution
title_full_unstemmed Lineage dynamics of murine pancreatic development at single-cell resolution
title_sort lineage dynamics of murine pancreatic development at single-cell resolution
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/9908253a395045fca4eafe9adba9fcf4
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