In situ photografting during direct laser writing in thermoplastic microchannels

Abstract A method for in situ photografting during direct laser writing by two-photon polymerization is presented. The technique serves as a powerful approach to the formation of covalent bonds between 3D photoresist structures and thermoplastic surfaces. By leveraging the same laser for both patter...

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Autores principales:	Jung Y. Han, Sarah Warshawsky, Don L. DeVoe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9916d9e9b5a9474fb58ed1e6c8182a9a
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spelling	oai:doaj.org-article:9916d9e9b5a9474fb58ed1e6c8182a9a2021-12-02T14:49:25ZIn situ photografting during direct laser writing in thermoplastic microchannels10.1038/s41598-021-90571-22045-2322https://doaj.org/article/9916d9e9b5a9474fb58ed1e6c8182a9a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90571-2https://doaj.org/toc/2045-2322Abstract A method for in situ photografting during direct laser writing by two-photon polymerization is presented. The technique serves as a powerful approach to the formation of covalent bonds between 3D photoresist structures and thermoplastic surfaces. By leveraging the same laser for both pattern generation and localized surface reactions, crosslinking between the bulk photoresist and thermoplastic surface is achieved during polymerization. When applied to in-channel direct laser writing for microfluidic device fabrication, the process yields exceptionally strong adhesion and robust bond interfaces that can withstand pressure gradients as high as 7 MPa through proper channel design, photoinitiator selection, and processing conditions.Jung Y. HanSarah WarshawskyDon L. DeVoeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jung Y. Han Sarah Warshawsky Don L. DeVoe In situ photografting during direct laser writing in thermoplastic microchannels
description	Abstract A method for in situ photografting during direct laser writing by two-photon polymerization is presented. The technique serves as a powerful approach to the formation of covalent bonds between 3D photoresist structures and thermoplastic surfaces. By leveraging the same laser for both pattern generation and localized surface reactions, crosslinking between the bulk photoresist and thermoplastic surface is achieved during polymerization. When applied to in-channel direct laser writing for microfluidic device fabrication, the process yields exceptionally strong adhesion and robust bond interfaces that can withstand pressure gradients as high as 7 MPa through proper channel design, photoinitiator selection, and processing conditions.
format	article
author	Jung Y. Han Sarah Warshawsky Don L. DeVoe
author_facet	Jung Y. Han Sarah Warshawsky Don L. DeVoe
author_sort	Jung Y. Han
title	In situ photografting during direct laser writing in thermoplastic microchannels
title_short	In situ photografting during direct laser writing in thermoplastic microchannels
title_full	In situ photografting during direct laser writing in thermoplastic microchannels
title_fullStr	In situ photografting during direct laser writing in thermoplastic microchannels
title_full_unstemmed	In situ photografting during direct laser writing in thermoplastic microchannels
title_sort	in situ photografting during direct laser writing in thermoplastic microchannels
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9916d9e9b5a9474fb58ed1e6c8182a9a
work_keys_str_mv	AT jungyhan insituphotograftingduringdirectlaserwritinginthermoplasticmicrochannels AT sarahwarshawsky insituphotograftingduringdirectlaserwritinginthermoplasticmicrochannels AT donldevoe insituphotograftingduringdirectlaserwritinginthermoplasticmicrochannels
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In situ photografting during direct laser writing in thermoplastic microchannels

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