A user's guide to the encyclopedia of DNA elements (ENCODE).

The mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the scientific and medical communities to interpret the human genome sequence and apply it to understand human biology and improve health. The ENCODE Consortium is integrating multiple technologies and approaches in a coll...

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Autor principal: ENCODE Project Consortium
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Publicado: Public Library of Science (PLoS) 2011
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spelling oai:doaj.org-article:991adc796dac42399fe2fe6faa5934852021-11-18T05:36:13ZA user's guide to the encyclopedia of DNA elements (ENCODE).1544-91731545-788510.1371/journal.pbio.1001046https://doaj.org/article/991adc796dac42399fe2fe6faa5934852011-04-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21526222/pdf/?tool=EBIhttps://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885The mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the scientific and medical communities to interpret the human genome sequence and apply it to understand human biology and improve health. The ENCODE Consortium is integrating multiple technologies and approaches in a collective effort to discover and define the functional elements encoded in the human genome, including genes, transcripts, and transcriptional regulatory regions, together with their attendant chromatin states and DNA methylation patterns. In the process, standards to ensure high-quality data have been implemented, and novel algorithms have been developed to facilitate analysis. Data and derived results are made available through a freely accessible database. Here we provide an overview of the project and the resources it is generating and illustrate the application of ENCODE data to interpret the human genome.ENCODE Project ConsortiumPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 9, Iss 4, p e1001046 (2011)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
ENCODE Project Consortium
A user's guide to the encyclopedia of DNA elements (ENCODE).
description The mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the scientific and medical communities to interpret the human genome sequence and apply it to understand human biology and improve health. The ENCODE Consortium is integrating multiple technologies and approaches in a collective effort to discover and define the functional elements encoded in the human genome, including genes, transcripts, and transcriptional regulatory regions, together with their attendant chromatin states and DNA methylation patterns. In the process, standards to ensure high-quality data have been implemented, and novel algorithms have been developed to facilitate analysis. Data and derived results are made available through a freely accessible database. Here we provide an overview of the project and the resources it is generating and illustrate the application of ENCODE data to interpret the human genome.
format article
author ENCODE Project Consortium
author_facet ENCODE Project Consortium
author_sort ENCODE Project Consortium
title A user's guide to the encyclopedia of DNA elements (ENCODE).
title_short A user's guide to the encyclopedia of DNA elements (ENCODE).
title_full A user's guide to the encyclopedia of DNA elements (ENCODE).
title_fullStr A user's guide to the encyclopedia of DNA elements (ENCODE).
title_full_unstemmed A user's guide to the encyclopedia of DNA elements (ENCODE).
title_sort user's guide to the encyclopedia of dna elements (encode).
publisher Public Library of Science (PLoS)
publishDate 2011
url https://doaj.org/article/991adc796dac42399fe2fe6faa593485
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