Functional screening for anti-CMV biologics identifies a broadly neutralizing epitope of an essential envelope protein

Human cytomegalovirus (CMV) poses a risk for immunosuppressed patients and newborns, with limited treatment options available. Here, Gardneret al. use a high-throughput approach and identify monoclonal antibodies that bind a highly conserved domain in the viral glycoprotein gH as potent inhibitors o...

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Auteurs principaux: Thomas J. Gardner, Kathryn R. Stein, J. Andrew Duty, Toni M. Schwarz, Vanessa M. Noriega, Thomas Kraus, Thomas M. Moran, Domenico Tortorella
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/991bb8c974f040b5b045baf0a89ab897
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