Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming

PFKFB3 enhances glycolysis to promote cancer cell proliferation. Here, the authors identify a long noncoding RNA in esophageal squamous cell carcinoma, AGPG, which interacts with PFKFB3 and promotes its stability, leading to increased glycolysis and proliferation.

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Autores principales:	Jia Liu, Ze-Xian Liu, Qi-Nian Wu, Yun-Xin Lu, Chau-Wei Wong, Lei Miao, Yun Wang, Zixian Wang, Ying Jin, Ming-Ming He, Chao Ren, De-Shen Wang, Dong-Liang Chen, Heng-Ying Pu, Lin Feng, Bo Li, Dan Xie, Mu-Sheng Zeng, Peng Huang, Aifu Lin, Dongxin Lin, Rui-Hua Xu, Huai-Qiang Ju
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/991c7443503b477c92252788160db378
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spelling	oai:doaj.org-article:991c7443503b477c92252788160db3782021-12-02T14:41:04ZLong noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming10.1038/s41467-020-15112-32041-1723https://doaj.org/article/991c7443503b477c92252788160db3782020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15112-3https://doaj.org/toc/2041-1723PFKFB3 enhances glycolysis to promote cancer cell proliferation. Here, the authors identify a long noncoding RNA in esophageal squamous cell carcinoma, AGPG, which interacts with PFKFB3 and promotes its stability, leading to increased glycolysis and proliferation.Jia LiuZe-Xian LiuQi-Nian WuYun-Xin LuChau-Wei WongLei MiaoYun WangZixian WangYing JinMing-Ming HeChao RenDe-Shen WangDong-Liang ChenHeng-Ying PuLin FengBo LiDan XieMu-Sheng ZengPeng HuangAifu LinDongxin LinRui-Hua XuHuai-Qiang JuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jia Liu Ze-Xian Liu Qi-Nian Wu Yun-Xin Lu Chau-Wei Wong Lei Miao Yun Wang Zixian Wang Ying Jin Ming-Ming He Chao Ren De-Shen Wang Dong-Liang Chen Heng-Ying Pu Lin Feng Bo Li Dan Xie Mu-Sheng Zeng Peng Huang Aifu Lin Dongxin Lin Rui-Hua Xu Huai-Qiang Ju Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
description	PFKFB3 enhances glycolysis to promote cancer cell proliferation. Here, the authors identify a long noncoding RNA in esophageal squamous cell carcinoma, AGPG, which interacts with PFKFB3 and promotes its stability, leading to increased glycolysis and proliferation.
format	article
author	Jia Liu Ze-Xian Liu Qi-Nian Wu Yun-Xin Lu Chau-Wei Wong Lei Miao Yun Wang Zixian Wang Ying Jin Ming-Ming He Chao Ren De-Shen Wang Dong-Liang Chen Heng-Ying Pu Lin Feng Bo Li Dan Xie Mu-Sheng Zeng Peng Huang Aifu Lin Dongxin Lin Rui-Hua Xu Huai-Qiang Ju
author_facet	Jia Liu Ze-Xian Liu Qi-Nian Wu Yun-Xin Lu Chau-Wei Wong Lei Miao Yun Wang Zixian Wang Ying Jin Ming-Ming He Chao Ren De-Shen Wang Dong-Liang Chen Heng-Ying Pu Lin Feng Bo Li Dan Xie Mu-Sheng Zeng Peng Huang Aifu Lin Dongxin Lin Rui-Hua Xu Huai-Qiang Ju
author_sort	Jia Liu
title	Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
title_short	Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
title_full	Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
title_fullStr	Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
title_full_unstemmed	Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
title_sort	long noncoding rna agpg regulates pfkfb3-mediated tumor glycolytic reprogramming
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/991c7443503b477c92252788160db378
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Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming

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