Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma

Liquid biopsies are emerging as a useful method for diagnosis and prognosis in cancer. Here, the authors show the prognostic value of monitoring the level of circulating Epstein-barr virus DNA throughout induction chemotherapy and chemo-radiotherapy and its potential utility for risk-adapted individ...

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Autores principales: Jiawei Lv, Yupei Chen, Guanqun Zhou, Zhenyu Qi, Kuan Rui Lloyd Tan, Haitao Wang, Li Lin, Foping Chen, Lulu Zhang, Xiaodan Huang, Ruiqi Liu, Sisi Xu, Yue Chen, Jun Ma, Melvin L. K. Chua, Ying Sun
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9928a95fca794df79074104762ef818c
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spelling oai:doaj.org-article:9928a95fca794df79074104762ef818c2021-12-02T14:35:36ZLiquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma10.1038/s41467-019-11853-y2041-1723https://doaj.org/article/9928a95fca794df79074104762ef818c2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11853-yhttps://doaj.org/toc/2041-1723Liquid biopsies are emerging as a useful method for diagnosis and prognosis in cancer. Here, the authors show the prognostic value of monitoring the level of circulating Epstein-barr virus DNA throughout induction chemotherapy and chemo-radiotherapy and its potential utility for risk-adapted individualised therapy in nasopharyngeal carcinomapatients.Jiawei LvYupei ChenGuanqun ZhouZhenyu QiKuan Rui Lloyd TanHaitao WangLi LinFoping ChenLulu ZhangXiaodan HuangRuiqi LiuSisi XuYue ChenJun MaMelvin L. K. ChuaYing SunNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jiawei Lv
Yupei Chen
Guanqun Zhou
Zhenyu Qi
Kuan Rui Lloyd Tan
Haitao Wang
Li Lin
Foping Chen
Lulu Zhang
Xiaodan Huang
Ruiqi Liu
Sisi Xu
Yue Chen
Jun Ma
Melvin L. K. Chua
Ying Sun
Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma
description Liquid biopsies are emerging as a useful method for diagnosis and prognosis in cancer. Here, the authors show the prognostic value of monitoring the level of circulating Epstein-barr virus DNA throughout induction chemotherapy and chemo-radiotherapy and its potential utility for risk-adapted individualised therapy in nasopharyngeal carcinomapatients.
format article
author Jiawei Lv
Yupei Chen
Guanqun Zhou
Zhenyu Qi
Kuan Rui Lloyd Tan
Haitao Wang
Li Lin
Foping Chen
Lulu Zhang
Xiaodan Huang
Ruiqi Liu
Sisi Xu
Yue Chen
Jun Ma
Melvin L. K. Chua
Ying Sun
author_facet Jiawei Lv
Yupei Chen
Guanqun Zhou
Zhenyu Qi
Kuan Rui Lloyd Tan
Haitao Wang
Li Lin
Foping Chen
Lulu Zhang
Xiaodan Huang
Ruiqi Liu
Sisi Xu
Yue Chen
Jun Ma
Melvin L. K. Chua
Ying Sun
author_sort Jiawei Lv
title Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma
title_short Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma
title_full Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma
title_fullStr Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma
title_full_unstemmed Liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma
title_sort liquid biopsy tracking during sequential chemo-radiotherapy identifies distinct prognostic phenotypes in nasopharyngeal carcinoma
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9928a95fca794df79074104762ef818c
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