Artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography

Abstract Rapid diagnosis of myocardial infarction (MI) using electrocardiography (ECG) is the cornerstone of effective treatment and prevention of mortality; however, conventional interpretation methods has low reliability for detecting MI and is difficulty to apply to limb 6-lead ECG based life typ...

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Autores principales: Younghoon Cho, Joon-myoung Kwon, Kyung-Hee Kim, Jose R. Medina-Inojosa, Ki-Hyun Jeon, Soohyun Cho, Soo Youn Lee, Jinsik Park, Byung-Hee Oh
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/9929d36a5ebe44cd8f13f0d280c39c94
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spelling oai:doaj.org-article:9929d36a5ebe44cd8f13f0d280c39c942021-12-02T12:34:18ZArtificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography10.1038/s41598-020-77599-62045-2322https://doaj.org/article/9929d36a5ebe44cd8f13f0d280c39c942020-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-77599-6https://doaj.org/toc/2045-2322Abstract Rapid diagnosis of myocardial infarction (MI) using electrocardiography (ECG) is the cornerstone of effective treatment and prevention of mortality; however, conventional interpretation methods has low reliability for detecting MI and is difficulty to apply to limb 6-lead ECG based life type or wearable devices. We developed and validated a deep learning-based artificial intelligence algorithm (DLA) for detecting MI using 6-lead ECG. A total of 412,461 ECGs were used to develop a variational autoencoder (VAE) that reconstructed precordial 6-lead ECG using limb 6-lead ECG. Data from 9536, 1301, and 1768 ECGs of adult patients who underwent coronary angiography within 24 h from each ECG were used for development, internal and external validation, respectively. During internal and external validation, the area under the receiver operating characteristic curves of the DLA with VAE using a 6-lead ECG were 0.880 and 0.854, respectively, and the performances were preserved by the territory of the coronary lesion. Our DLA successfully detected MI using a 12-lead ECG or a 6-lead ECG. The results indicate that MI could be detected not only with a conventional 12 lead ECG but also with a life type 6-lead ECG device that employs our DLA.Younghoon ChoJoon-myoung KwonKyung-Hee KimJose R. Medina-InojosaKi-Hyun JeonSoohyun ChoSoo Youn LeeJinsik ParkByung-Hee OhNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Younghoon Cho
Joon-myoung Kwon
Kyung-Hee Kim
Jose R. Medina-Inojosa
Ki-Hyun Jeon
Soohyun Cho
Soo Youn Lee
Jinsik Park
Byung-Hee Oh
Artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography
description Abstract Rapid diagnosis of myocardial infarction (MI) using electrocardiography (ECG) is the cornerstone of effective treatment and prevention of mortality; however, conventional interpretation methods has low reliability for detecting MI and is difficulty to apply to limb 6-lead ECG based life type or wearable devices. We developed and validated a deep learning-based artificial intelligence algorithm (DLA) for detecting MI using 6-lead ECG. A total of 412,461 ECGs were used to develop a variational autoencoder (VAE) that reconstructed precordial 6-lead ECG using limb 6-lead ECG. Data from 9536, 1301, and 1768 ECGs of adult patients who underwent coronary angiography within 24 h from each ECG were used for development, internal and external validation, respectively. During internal and external validation, the area under the receiver operating characteristic curves of the DLA with VAE using a 6-lead ECG were 0.880 and 0.854, respectively, and the performances were preserved by the territory of the coronary lesion. Our DLA successfully detected MI using a 12-lead ECG or a 6-lead ECG. The results indicate that MI could be detected not only with a conventional 12 lead ECG but also with a life type 6-lead ECG device that employs our DLA.
format article
author Younghoon Cho
Joon-myoung Kwon
Kyung-Hee Kim
Jose R. Medina-Inojosa
Ki-Hyun Jeon
Soohyun Cho
Soo Youn Lee
Jinsik Park
Byung-Hee Oh
author_facet Younghoon Cho
Joon-myoung Kwon
Kyung-Hee Kim
Jose R. Medina-Inojosa
Ki-Hyun Jeon
Soohyun Cho
Soo Youn Lee
Jinsik Park
Byung-Hee Oh
author_sort Younghoon Cho
title Artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography
title_short Artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography
title_full Artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography
title_fullStr Artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography
title_full_unstemmed Artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography
title_sort artificial intelligence algorithm for detecting myocardial infarction using six-lead electrocardiography
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/9929d36a5ebe44cd8f13f0d280c39c94
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