Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase

As part of two-component systems, diguanylate cyclases (DGCs) are activated by phosphorylation. Structural and computational analyses of DgcR, a model DGC, reveal the phosphorylation-induced conformational changes and the activation mechanism likely shared by many DGCs with N-terminal coiled-coil li...

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Bibliographic Details
Main Authors: Raphael D. Teixeira, Fabian Holzschuh, Tilman Schirmer
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/993709a2a8174e36ab5ef612d935d41e
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