SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

Regulatory T cells are crucial for the establishment and maintenance of peripheral immune tolerance, yet the mechanisms regulating their stability and function remain to be fully elucidated. Here the authors show SENP3 maintains Treg cell stability and function via BACH2 deSUMOylation.

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Autores principales:	Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo, Siyu Deng, Yuzhou Chang, Xuefeng Wu, Zhiduo Liu, Lei Chen, Li-Ming Lu, Jinke Cheng, Bin Li, Bing Su, Jin Jiang, Hua-Bing Li, Chuanxin Huang, Jing Yi, Qiang Zou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/99392c4923a841bda11bc7886d22d63c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:99392c4923a841bda11bc7886d22d63c2021-12-02T15:34:03ZSENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation10.1038/s41467-018-05676-62041-1723https://doaj.org/article/99392c4923a841bda11bc7886d22d63c2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05676-6https://doaj.org/toc/2041-1723Regulatory T cells are crucial for the establishment and maintenance of peripheral immune tolerance, yet the mechanisms regulating their stability and function remain to be fully elucidated. Here the authors show SENP3 maintains Treg cell stability and function via BACH2 deSUMOylation.Xiaoyan YuYimin LaoXiao-Lu TengSong LiYan ZhouFeixiang WangXinwei GuoSiyu DengYuzhou ChangXuefeng WuZhiduo LiuLei ChenLi-Ming LuJinke ChengBin LiBing SuJin JiangHua-Bing LiChuanxin HuangJing YiQiang ZouNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaoyan Yu Yimin Lao Xiao-Lu Teng Song Li Yan Zhou Feixiang Wang Xinwei Guo Siyu Deng Yuzhou Chang Xuefeng Wu Zhiduo Liu Lei Chen Li-Ming Lu Jinke Cheng Bin Li Bing Su Jin Jiang Hua-Bing Li Chuanxin Huang Jing Yi Qiang Zou SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
description	Regulatory T cells are crucial for the establishment and maintenance of peripheral immune tolerance, yet the mechanisms regulating their stability and function remain to be fully elucidated. Here the authors show SENP3 maintains Treg cell stability and function via BACH2 deSUMOylation.
format	article
author	Xiaoyan Yu Yimin Lao Xiao-Lu Teng Song Li Yan Zhou Feixiang Wang Xinwei Guo Siyu Deng Yuzhou Chang Xuefeng Wu Zhiduo Liu Lei Chen Li-Ming Lu Jinke Cheng Bin Li Bing Su Jin Jiang Hua-Bing Li Chuanxin Huang Jing Yi Qiang Zou
author_facet	Xiaoyan Yu Yimin Lao Xiao-Lu Teng Song Li Yan Zhou Feixiang Wang Xinwei Guo Siyu Deng Yuzhou Chang Xuefeng Wu Zhiduo Liu Lei Chen Li-Ming Lu Jinke Cheng Bin Li Bing Su Jin Jiang Hua-Bing Li Chuanxin Huang Jing Yi Qiang Zou
author_sort	Xiaoyan Yu
title	SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
title_short	SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
title_full	SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
title_fullStr	SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
title_full_unstemmed	SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
title_sort	senp3 maintains the stability and function of regulatory t cells via bach2 desumoylation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/99392c4923a841bda11bc7886d22d63c
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SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

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