SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

Regulatory T cells are crucial for the establishment and maintenance of peripheral immune tolerance, yet the mechanisms regulating their stability and function remain to be fully elucidated. Here the authors show SENP3 maintains Treg cell stability and function via BACH2 deSUMOylation.

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Bibliographic Details
Main Authors: Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo, Siyu Deng, Yuzhou Chang, Xuefeng Wu, Zhiduo Liu, Lei Chen, Li-Ming Lu, Jinke Cheng, Bin Li, Bing Su, Jin Jiang, Hua-Bing Li, Chuanxin Huang, Jing Yi, Qiang Zou
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/99392c4923a841bda11bc7886d22d63c
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https://doaj.org/article/99392c4923a841bda11bc7886d22d63c

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