Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR).
<h4>Background</h4>Abnormal germline DNA methylation in males has been proposed as a possible mechanism compromising spermatogenesis of some men currently diagnosed with idiopathic infertility. Previous studies have been focused on imprinted genes with DNA methylation in poor quality hum...
Guardado en:
Autores principales: | Wei Wu, Ouxi Shen, Yufeng Qin, Xiaobing Niu, Chuncheng Lu, Yankai Xia, Ling Song, Shoulin Wang, Xinru Wang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/993fa77e712a46a3878527b8a0f360e3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Folate metabolism gene 5,10-methylenetetrahydrofolate reductase (MTHFR) is associated with ADHD in myelomeningocele patients.
por: Catherine J Spellicy, et al.
Publicado: (2012) -
The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China.
por: Zhen Li, et al.
Publicado: (2021) -
Methylenetetrahydrofolate reductase gene polymorphism and risk of type 2 diabetes mellitus.
por: Jian-Hong Zhong, et al.
Publicado: (2013) -
Effects of methylenetetrahydrofolate reductase single-nucleotide polymorphisms on breast, cervical, ovarian, and endometrial cancer susceptibilities
por: Zheng Wang, et al.
Publicado: (2021) -
Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition
por: D. Sean Froese, et al.
Publicado: (2018)