Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR).
<h4>Background</h4>Abnormal germline DNA methylation in males has been proposed as a possible mechanism compromising spermatogenesis of some men currently diagnosed with idiopathic infertility. Previous studies have been focused on imprinted genes with DNA methylation in poor quality hum...
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Auteurs principaux: | Wei Wu, Ouxi Shen, Yufeng Qin, Xiaobing Niu, Chuncheng Lu, Yankai Xia, Ling Song, Shoulin Wang, Xinru Wang |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
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Accès en ligne: | https://doaj.org/article/993fa77e712a46a3878527b8a0f360e3 |
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