Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR).

<h4>Background</h4>Abnormal germline DNA methylation in males has been proposed as a possible mechanism compromising spermatogenesis of some men currently diagnosed with idiopathic infertility. Previous studies have been focused on imprinted genes with DNA methylation in poor quality hum...

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Bibliographic Details
Main Authors: Wei Wu, Ouxi Shen, Yufeng Qin, Xiaobing Niu, Chuncheng Lu, Yankai Xia, Ling Song, Shoulin Wang, Xinru Wang
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
R
Q
Online Access:https://doaj.org/article/993fa77e712a46a3878527b8a0f360e3
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