Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A

Abstract Semaphorin 3A (Sema3A), a secreted member of the Semaphorin family, increases osteoblast differentiation, stimulates bone formation and enhances fracture healing. Here, we report a previously unknown role of Sema3A in the regulation of ectopic bone formation and osteolysis related to osteos...

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Autores principales: Daniëlle de Ridder, Silvia Marino, Ryan T. Bishop, Nathalie Renema, Chantal Chenu, Dominique Heymann, Aymen I. Idris
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/994150735f414fcf99e03f4cca7c2b49
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