Localization of damage in the human leg muscles induced by downhill running

Abstract We investigated localization of damage within the knee extensors (KEs) and plantar flexors (PFs) induced by downhill running (DR) by using transverse relaxation time (T2)-weighted magnetic resonance imaging (MRI). Fourteen young adults performed 45-min DR (−15% slope) at their maximal toler...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sumiaki Maeo, Yukino Ando, Hiroaki Kanehisa, Yasuo Kawakami
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9954e53e0f8643a5a57d6d3964b413c2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9954e53e0f8643a5a57d6d3964b413c2
record_format	dspace
spelling	oai:doaj.org-article:9954e53e0f8643a5a57d6d3964b413c22021-12-02T12:32:06ZLocalization of damage in the human leg muscles induced by downhill running10.1038/s41598-017-06129-82045-2322https://doaj.org/article/9954e53e0f8643a5a57d6d3964b413c22017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06129-8https://doaj.org/toc/2045-2322Abstract We investigated localization of damage within the knee extensors (KEs) and plantar flexors (PFs) induced by downhill running (DR) by using transverse relaxation time (T2)-weighted magnetic resonance imaging (MRI). Fourteen young adults performed 45-min DR (−15% slope) at their maximal tolerable velocity. At pre- and 24, 48, and 72 h post-exercise, T2-MRI was scanned and T2 values for each muscle composing KEs and PFs at proximal, middle, and distal sites were calculated. Maximal isometric torque and rate of torque development (RTD: 0–30, 0–50, 0–100, 0–200 ms) were also measured. Maximal torque significantly decreased in KEs (14–17%) and PFs (6–8%) at 24–48 h post-exercise, with greater reductions for KEs. RTD in all phases, except for 0–200 ms in PFs, significantly decreased in KEs (11–42%) and PFs (13–23%) at least at one time point post-exercise. T2 significantly increased at several sites (3–5%) in both muscle groups at 24 and/or 48 h post-exercise. Among the T2-increased sites, the peak effect size (Cohen’s d) regarding T2 change was pronounced at proximal (1.05) and middle (1.64) vastus intermedius compared to the other sites (0.72–0.77). These results suggest that DR induces damage in both KEs and PFs, and especially affects proximal–middle sites of the vastus intermedius.Sumiaki MaeoYukino AndoHiroaki KanehisaYasuo KawakamiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sumiaki Maeo Yukino Ando Hiroaki Kanehisa Yasuo Kawakami Localization of damage in the human leg muscles induced by downhill running
description	Abstract We investigated localization of damage within the knee extensors (KEs) and plantar flexors (PFs) induced by downhill running (DR) by using transverse relaxation time (T2)-weighted magnetic resonance imaging (MRI). Fourteen young adults performed 45-min DR (−15% slope) at their maximal tolerable velocity. At pre- and 24, 48, and 72 h post-exercise, T2-MRI was scanned and T2 values for each muscle composing KEs and PFs at proximal, middle, and distal sites were calculated. Maximal isometric torque and rate of torque development (RTD: 0–30, 0–50, 0–100, 0–200 ms) were also measured. Maximal torque significantly decreased in KEs (14–17%) and PFs (6–8%) at 24–48 h post-exercise, with greater reductions for KEs. RTD in all phases, except for 0–200 ms in PFs, significantly decreased in KEs (11–42%) and PFs (13–23%) at least at one time point post-exercise. T2 significantly increased at several sites (3–5%) in both muscle groups at 24 and/or 48 h post-exercise. Among the T2-increased sites, the peak effect size (Cohen’s d) regarding T2 change was pronounced at proximal (1.05) and middle (1.64) vastus intermedius compared to the other sites (0.72–0.77). These results suggest that DR induces damage in both KEs and PFs, and especially affects proximal–middle sites of the vastus intermedius.
format	article
author	Sumiaki Maeo Yukino Ando Hiroaki Kanehisa Yasuo Kawakami
author_facet	Sumiaki Maeo Yukino Ando Hiroaki Kanehisa Yasuo Kawakami
author_sort	Sumiaki Maeo
title	Localization of damage in the human leg muscles induced by downhill running
title_short	Localization of damage in the human leg muscles induced by downhill running
title_full	Localization of damage in the human leg muscles induced by downhill running
title_fullStr	Localization of damage in the human leg muscles induced by downhill running
title_full_unstemmed	Localization of damage in the human leg muscles induced by downhill running
title_sort	localization of damage in the human leg muscles induced by downhill running
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9954e53e0f8643a5a57d6d3964b413c2
work_keys_str_mv	AT sumiakimaeo localizationofdamageinthehumanlegmusclesinducedbydownhillrunning AT yukinoando localizationofdamageinthehumanlegmusclesinducedbydownhillrunning AT hiroakikanehisa localizationofdamageinthehumanlegmusclesinducedbydownhillrunning AT yasuokawakami localizationofdamageinthehumanlegmusclesinducedbydownhillrunning
_version_	1718394173802938368

Localization of damage in the human leg muscles induced by downhill running

Ejemplares similares