NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels.

Short-chain quinones are described as potent antioxidants and in the case of idebenone have already been under clinical investigation for the treatment of neuromuscular disorders. Due to their analogy to coenzyme Q10 (CoQ10), a long-chain quinone, they are widely regarded as a substitute for CoQ10....

Full description

Saved in:
Bibliographic Details
Main Authors: Roman H Haefeli, Michael Erb, Anja C Gemperli, Dimitri Robay, Isabelle Courdier Fruh, Corinne Anklin, Robert Dallmann, Nuri Gueven
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/995afdd9e07d4e6a8cbf10a94635935c
Tags: Add Tag
No Tags, Be the first to tag this record!