Optical imaging of single-protein size, charge, mobility, and binding
Protein identification at the single-molecule level is the ultimate goal for biological research and disease diagnosis. Here, the authors identify the size, charge, mobility, and binding of individual protein molecules by measuring the optical and electrical responses of each protein molecule tether...
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Nature Portfolio
2020
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oai:doaj.org-article:99808efcbbbb4331a607d437ec1b05bd2021-12-02T15:15:06ZOptical imaging of single-protein size, charge, mobility, and binding10.1038/s41467-020-18547-w2041-1723https://doaj.org/article/99808efcbbbb4331a607d437ec1b05bd2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18547-whttps://doaj.org/toc/2041-1723Protein identification at the single-molecule level is the ultimate goal for biological research and disease diagnosis. Here, the authors identify the size, charge, mobility, and binding of individual protein molecules by measuring the optical and electrical responses of each protein molecule tethered to a surface.Guangzhong MaZijian WanYunze YangPengfei ZhangShaopeng WangNongjian TaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Guangzhong Ma Zijian Wan Yunze Yang Pengfei Zhang Shaopeng Wang Nongjian Tao Optical imaging of single-protein size, charge, mobility, and binding |
description |
Protein identification at the single-molecule level is the ultimate goal for biological research and disease diagnosis. Here, the authors identify the size, charge, mobility, and binding of individual protein molecules by measuring the optical and electrical responses of each protein molecule tethered to a surface. |
format |
article |
author |
Guangzhong Ma Zijian Wan Yunze Yang Pengfei Zhang Shaopeng Wang Nongjian Tao |
author_facet |
Guangzhong Ma Zijian Wan Yunze Yang Pengfei Zhang Shaopeng Wang Nongjian Tao |
author_sort |
Guangzhong Ma |
title |
Optical imaging of single-protein size, charge, mobility, and binding |
title_short |
Optical imaging of single-protein size, charge, mobility, and binding |
title_full |
Optical imaging of single-protein size, charge, mobility, and binding |
title_fullStr |
Optical imaging of single-protein size, charge, mobility, and binding |
title_full_unstemmed |
Optical imaging of single-protein size, charge, mobility, and binding |
title_sort |
optical imaging of single-protein size, charge, mobility, and binding |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/99808efcbbbb4331a607d437ec1b05bd |
work_keys_str_mv |
AT guangzhongma opticalimagingofsingleproteinsizechargemobilityandbinding AT zijianwan opticalimagingofsingleproteinsizechargemobilityandbinding AT yunzeyang opticalimagingofsingleproteinsizechargemobilityandbinding AT pengfeizhang opticalimagingofsingleproteinsizechargemobilityandbinding AT shaopengwang opticalimagingofsingleproteinsizechargemobilityandbinding AT nongjiantao opticalimagingofsingleproteinsizechargemobilityandbinding |
_version_ |
1718387586063400960 |