Optical imaging of single-protein size, charge, mobility, and binding

Protein identification at the single-molecule level is the ultimate goal for biological research and disease diagnosis. Here, the authors identify the size, charge, mobility, and binding of individual protein molecules by measuring the optical and electrical responses of each protein molecule tether...

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Autores principales: Guangzhong Ma, Zijian Wan, Yunze Yang, Pengfei Zhang, Shaopeng Wang, Nongjian Tao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/99808efcbbbb4331a607d437ec1b05bd
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spelling oai:doaj.org-article:99808efcbbbb4331a607d437ec1b05bd2021-12-02T15:15:06ZOptical imaging of single-protein size, charge, mobility, and binding10.1038/s41467-020-18547-w2041-1723https://doaj.org/article/99808efcbbbb4331a607d437ec1b05bd2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18547-whttps://doaj.org/toc/2041-1723Protein identification at the single-molecule level is the ultimate goal for biological research and disease diagnosis. Here, the authors identify the size, charge, mobility, and binding of individual protein molecules by measuring the optical and electrical responses of each protein molecule tethered to a surface.Guangzhong MaZijian WanYunze YangPengfei ZhangShaopeng WangNongjian TaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Guangzhong Ma
Zijian Wan
Yunze Yang
Pengfei Zhang
Shaopeng Wang
Nongjian Tao
Optical imaging of single-protein size, charge, mobility, and binding
description Protein identification at the single-molecule level is the ultimate goal for biological research and disease diagnosis. Here, the authors identify the size, charge, mobility, and binding of individual protein molecules by measuring the optical and electrical responses of each protein molecule tethered to a surface.
format article
author Guangzhong Ma
Zijian Wan
Yunze Yang
Pengfei Zhang
Shaopeng Wang
Nongjian Tao
author_facet Guangzhong Ma
Zijian Wan
Yunze Yang
Pengfei Zhang
Shaopeng Wang
Nongjian Tao
author_sort Guangzhong Ma
title Optical imaging of single-protein size, charge, mobility, and binding
title_short Optical imaging of single-protein size, charge, mobility, and binding
title_full Optical imaging of single-protein size, charge, mobility, and binding
title_fullStr Optical imaging of single-protein size, charge, mobility, and binding
title_full_unstemmed Optical imaging of single-protein size, charge, mobility, and binding
title_sort optical imaging of single-protein size, charge, mobility, and binding
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/99808efcbbbb4331a607d437ec1b05bd
work_keys_str_mv AT guangzhongma opticalimagingofsingleproteinsizechargemobilityandbinding
AT zijianwan opticalimagingofsingleproteinsizechargemobilityandbinding
AT yunzeyang opticalimagingofsingleproteinsizechargemobilityandbinding
AT pengfeizhang opticalimagingofsingleproteinsizechargemobilityandbinding
AT shaopengwang opticalimagingofsingleproteinsizechargemobilityandbinding
AT nongjiantao opticalimagingofsingleproteinsizechargemobilityandbinding
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